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20 Cards in this Set

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  • Back
Phenol
Disruption of plasma membrane, denaturation of enzymes. Rarely used.
Phenolic
Disruption of plasma membrane, denaturation of enzymes. Environmental surfaces, instruments, skin surfaces, and mucous membranes.
What are the advantages of pheolics over phenol?
1. Nonirritating
2. Relatively Odorless
3. More Effective
4. Less Toxic
Ex: cresols (Lysol) hexacholorphene (pHisoHex)
Biguanides
chlorhexidine
What are examples of halogens?
Iodine (tincture of iodine, betadine, and isodine), chlorine, calcium hypochlorite, sodium hypochlorite (bleach, clorox), choramines
Alcohols
Usually act by denaturing protein in the pathogens. This action is also the reason why they are poor antiseptics when applied to wounds since they will coagulate (denature) a layer of protein in the would in which the bacteria will contiune to grow.
What are two types of alcohol?
Ethanol & Isopropal
How is isopropal better than ethanol?
Better as an antiseptic and disinfectant since it is less volatile, less expensive, and more easily obtained.
What are heavy metals and their componants?
Silver in silver nitrate, mercuric chloride, copper sulfate, zinc chloride.
soap
least effective antimicrobial agent but is important to wash hands for the mechanical removal of microbes.
Quaternary ammounium Compounds (Quats)
these are cationic detergents and are the most widely used surface active agents. Effective againstgram positive bacteria and gram negatives to some degree.
Are quats amoebecidal, vicuical (enveloped viruses), and fungicidal
YES
Do quats kill endosporesor tuberculosis bacteria
NO
Examples of quats
Zephhiran and Cepactol (If your mouthwash foams when you shake it, it contains quat.
Examples of Organce acid and their derivatives (chemical good preserv)
sodium benzoate, sorbic acid, calcium propinate
Aldehyes
formaldehyde and glutaraldehyde
gaseous chemosterilizers
gas frequently used in ethylene oxide
peroxygens
oxidizing agents
Examples of peroxygens
hydrogen pyroxide. ozone, benzoyl peroxide
What is hydrogen peroxide not a good antiseptic?
because it is broken down by catalase to produce water & oxygen