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35 Cards in this Set

  • Front
  • Back

Liver

Largest organ. Functions: 1.metabolism of substances via portal vein. 2.synthesis (blood clotting, storage of vit B) 3. detox and excretion

Biliary Tree

A system of ducts acts to drain bile produced in the liver into the duodenum.

Biliary Tree Function

Store and concentrate bile that has been produced in the liver

Pancreas

Powerful digestive organ.

Exocrine function in Pancreas

(Trypsin) Relating to external secretions glands, such as sweat glands or salivary glands that release a secretion through a duct to the surface of an organ.

Endocrine function in Pancreas

(Insulin and Glucagon) group of cells secrete into blood or lymph circulating a substance (hormone) that has a specific effect on tissues in another part of the body

Gallbladder

Store and concentrate bile

Imaging considerations




Percutaneous Transhepatic Cholangiopgraphy


(PTC)

Needle through skin, through liver, to gallbladder




-Used to visualize biliary tree..


-Used to detect calculi or tumor in distal common bile duct

Imaging considerations




Endoscopic Retrograde Cholangiopancreatogram (ERCP)

-Used to visualize biliary system and main pancreatic duct


-Used o visualize nondilated ducts, distal obstructions, bleeding disorders, and pancreas

Imaging considerations




Operative Cholangiography

-Performed during surgery at time of cholecystectomy to detect biliary calculi and the need for common bile ducts exploration

Imaging considerations




T-tube Cholangiopgraphy

-Used after a cholecystectomy to demonstrate patency (openess) of the common bile duct and to check for calculi

Imaging considerations




Ultrasound

-Detect gallstones


(1 cm easily found)

Imaging considerations




CT

Following malignancies and assessing masses (Gallbladder, liver , and pancreas)




-Evaluation complications of cholecystitis

Imaging considerations




Nuclear Medicine

SPECT - hepatobiliary lesions




Cholescintigraphy scans- distinguish acute from chronic cholecystitis

Imaging considerations




MRI

-Visualize gallbladder and biliary system




w/ CT- evaluate abnormalities of peritoneum

Alcohol- Inducted Liver Disease

(toxin to liver)


-When metabolized by liver it results in cellular damage


-Oxidation results in reduced gluconeogenesis (reduced glucose) and inc. fatty acid synthesis

Fatty Liver Infiltration

-Chronic alcohol abuse leads to fatty liver, cirrhosis, and hepatocellular carcinoma (liver cancer)


-most frequent response to alcohol abuse


-usually asymptomatic, but most have hepatomegaly (enlarged liver)

Cirrhosis

-Chronic liver condition, early stage asymptomatic




-Parenchyma (functional tissue of liver) and architecture are destroyed =dying




-Impaired liver function and portal hypertension (pressure build up)



Ascites

Result of portal hypertension (pressure build up) and leakage of excessive fluids from portal capillaries




-Result from chronic hepatitis (liver), CHF, renal failure, and certain cancers




-Treatment= paracentesis (remove fluid from abdomen)

Viral Hepatitis Evidence

Common liver condition




-vomiting


-tenderness over liver (inflammation)


-fatigue


-anorexia


-photophobia


-malaise

Hepatitis A


(HAV)

-fecal in GI tract


-spread by contact


-short term sickness

Hepatitis B


(HBV)

-vaccinated against as a kid


-not common


-spread by serum and blood

Hepatitis C


(HCV)

-more common


-sexual contact/ blood transfusion/ needles


-may cause acute or chronic


-no treatment

Cholelithiasis


(Gallstones)

-very common in women


-surgically removed (cholecystectomy)


-acute onset pain and fever




-untreated= peritonitis, rupture

Panreatitis

-irreversible damages


-causes: alcohol abuse, obstruction of the ampulla of vater (opening of duct)




-diagnosed with ERCP and lab tests

Pancreatitis Symptomss

-pain


-nausea/ vomiting


-severe pain


-shock

Jaundice

Yellowish bile pigment

Jaundice




Medical vs. Surgical

Medical (nonobstructive)- *children* caused by hepatocellular dysfunction....


-too many red blood cells are destroyed/ too much damage from cirrhosis/ hepatitis




Surgical (obstructive)- biliary system is obstructive and stops bile from entering duodenum

Hepatocellular Adenoma



(liver)



Benign tumor of liver




-Occurs most often in women using oral contraceptives (birth control pill)

Hemangioma

Most common liver tumor




Benign neoplasm of newly formed blood vessels




Generally not malignant

Hepatocellular Carcinoma


(Hepatoma)

Malignant neoplasm in liver




-surgical resection vs. ablation

Metastatic Liver Disease

-More common than primary carcinoma due to livers role of filtering blood




-CT and MRI for staging


-Ultrasound for screening


-Biopsy for diagnosis

Carcinoma of Gallbladder

-infrequent


-gallstones are common


-RUQ pain


-Results from Cholecystitis


-low survival rate

Carcinoma in Pancreas

-rapidly fatal


-5th most common cause of cancer death


-diagnosis is difficult due to location of pancreas


-treatment: surgical resection


-cause: alcohol

Good Job! You're done with Chapter 5

:)