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36 Cards in this Set
- Front
- Back
What is the Autonomic Nervous System?
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The part of the nervous system that controls involuntary (automatic) actions.
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What is autonomic ganglia?
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Groups of autonomic nerve cells located outside the central nervous system.
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What are preganglonic nerves?
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Nerve fibers that extend from the central nervous system to the autonomic ganglia.
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What are postganglionic nerves?
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Nerve fibers that extend from the autonomic ganglia to the target tissues.
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Explain what a neurotransmitter is?
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A chemical messenger that conducts a nervous impulse across a synapse.
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Synapse that use acetylcholine as the neurotransmitter are ------ synapses.
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Cholinergic
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What does adrenergic mean?
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Pertains to the neurotransmitter norepinephrine.
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Parasympathomimetic
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Drug or other substance that causes effects like those of the parasympathetic nervous system (also called cholinergic)
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Parasympatholytic
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Drug or other substance that blocks or inhibits the actions of the parasympathetic nervous system (also called anticholinergic)
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What does SLUDGE stand for?
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Salivation
Lacrimation Urination Defecation Gastric Motility Emesis |
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What are the two basic types of indirect-acting cholinergic drugs?
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Reversible inhibitors and irreversible inhibitors
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What is the difference between reversible inhibitors and irreversible inhibitors?
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How long they remain bound to cholinesterase.
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What is Neostigmine (prostigmin)?
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It is the prototype reversible cholinesterase inhibitor.
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Irreversible cholinesterase inhibitors have only one clinical function, what does it treat?
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Glaucoma
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Muscarinic Cholinergic Antagonists are?
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Cholinergic antagonists that block the effect of acetylcholine exclusively at the muscarinic receptors.
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What is the prototype anticholinergic drug?
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Atropine
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Atropine is classified as what kind of drug?
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Belladonna alkaloids
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List four types of parasympathetic acetylcholine receptors.
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Muscarinic
Nicotinic Nicotinic n (neuron) Nicotinic m (muscle) |
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Nicotinic Cholinergic Antagonists block what and where?
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They block acetylcholine only at nicotinic sites.
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Neuromuscular blockers affect?
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Nicotinic m receptors
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What do neuromuscular blocking agents.
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Neuromuscular blockade produces a state of paralysis without affecting consciousness.
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The sympathetic nervous system releases norepinephrine and epinephrine from where?
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Norepinephrine- postganglionic end terminals
Epinephrine- adrenal medulla |
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Beta-adrenergic antagonists are more commonly referred to as?
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Beta Blockers
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Drugs used to affect parasympathetic nervous system.
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Cholinergics (parasympathomimetics)
Anticholinergics (parasympatholytics) Ganglionic Blocking Agents Neuromuscular Blocking Agent Ganglionic Stimulating Agents |
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Drugs used to affect sympathetic nervous system.
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Drugs that stimulate sympathetic nervous system are sympathomimetics and ones that inhibit system are sympatholytics.
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List classes of cardiovascular drugs
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Antidysrhythmics
Antihypertensives Hemostatic Agents Antihyperlipidemic Agents |
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In the list of cardiovascular drugs, What drugs fall under category of antidysrhythmics?
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Sodium Channel Blockers (Class I)
Beta Blockers (Class II) Potassium Channel Blockers (Class III) Calcium Channel Blockers (Class IV) |
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Cardiovascular Drugs, What drugs fall under antihypertensives?
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Diuretics
Angiotensin II Receptor Antagonists Calcium Channel Blocking Agents Direct Vasodilators |
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Cardiovascular Drugs, What drugs are Hemostatic Agents?
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Antiplatelets
Anticoagulants Fibrinolytics |
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What is a hyperlipidemic?
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Drug used to treat high blood cholesterol.
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What drug was first used clinically in 1879?
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Nitroglycerin
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What are the 3 calcium channel blockers most frequently used?
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Verapamil (Calan, Isoptin),
Diltiazen (Cardizem), Nifedipine (Procardia) |
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What is hemostasis?
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The stoppage of bleeding.
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What is an anticoagulant?
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Drug that interrupts the clotting cascade.
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What is an antiplatelet?
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Drug that decreases the formation of platelet plugs
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What is a fibrinolytic?
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Drug that acts directly on thrombi to break them down; also called thrombolytic.
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