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36 Cards in this Set

  • Front
  • Back
What is the Autonomic Nervous System?
The part of the nervous system that controls involuntary (automatic) actions.
What is autonomic ganglia?
Groups of autonomic nerve cells located outside the central nervous system.
What are preganglonic nerves?
Nerve fibers that extend from the central nervous system to the autonomic ganglia.
What are postganglionic nerves?
Nerve fibers that extend from the autonomic ganglia to the target tissues.
Explain what a neurotransmitter is?
A chemical messenger that conducts a nervous impulse across a synapse.
Synapse that use acetylcholine as the neurotransmitter are ------ synapses.
Cholinergic
What does adrenergic mean?
Pertains to the neurotransmitter norepinephrine.
Parasympathomimetic
Drug or other substance that causes effects like those of the parasympathetic nervous system (also called cholinergic)
Parasympatholytic
Drug or other substance that blocks or inhibits the actions of the parasympathetic nervous system (also called anticholinergic)
What does SLUDGE stand for?
Salivation
Lacrimation
Urination
Defecation
Gastric Motility
Emesis
What are the two basic types of indirect-acting cholinergic drugs?
Reversible inhibitors and irreversible inhibitors
What is the difference between reversible inhibitors and irreversible inhibitors?
How long they remain bound to cholinesterase.
What is Neostigmine (prostigmin)?
It is the prototype reversible cholinesterase inhibitor.
Irreversible cholinesterase inhibitors have only one clinical function, what does it treat?
Glaucoma
Muscarinic Cholinergic Antagonists are?
Cholinergic antagonists that block the effect of acetylcholine exclusively at the muscarinic receptors.
What is the prototype anticholinergic drug?
Atropine
Atropine is classified as what kind of drug?
Belladonna alkaloids
List four types of parasympathetic acetylcholine receptors.
Muscarinic
Nicotinic
Nicotinic n (neuron)
Nicotinic m (muscle)
Nicotinic Cholinergic Antagonists block what and where?
They block acetylcholine only at nicotinic sites.
Neuromuscular blockers affect?
Nicotinic m receptors
What do neuromuscular blocking agents.
Neuromuscular blockade produces a state of paralysis without affecting consciousness.
The sympathetic nervous system releases norepinephrine and epinephrine from where?
Norepinephrine- postganglionic end terminals
Epinephrine- adrenal medulla
Beta-adrenergic antagonists are more commonly referred to as?
Beta Blockers
Drugs used to affect parasympathetic nervous system.
Cholinergics (parasympathomimetics)
Anticholinergics (parasympatholytics)
Ganglionic Blocking Agents
Neuromuscular Blocking Agent
Ganglionic Stimulating Agents
Drugs used to affect sympathetic nervous system.
Drugs that stimulate sympathetic nervous system are sympathomimetics and ones that inhibit system are sympatholytics.
List classes of cardiovascular drugs
Antidysrhythmics
Antihypertensives
Hemostatic Agents
Antihyperlipidemic Agents
In the list of cardiovascular drugs, What drugs fall under category of antidysrhythmics?
Sodium Channel Blockers (Class I)
Beta Blockers (Class II)
Potassium Channel Blockers (Class III)
Calcium Channel Blockers (Class IV)
Cardiovascular Drugs, What drugs fall under antihypertensives?
Diuretics
Angiotensin II Receptor Antagonists
Calcium Channel Blocking Agents
Direct Vasodilators
Cardiovascular Drugs, What drugs are Hemostatic Agents?
Antiplatelets
Anticoagulants
Fibrinolytics
What is a hyperlipidemic?
Drug used to treat high blood cholesterol.
What drug was first used clinically in 1879?
Nitroglycerin
What are the 3 calcium channel blockers most frequently used?
Verapamil (Calan, Isoptin),
Diltiazen (Cardizem),
Nifedipine (Procardia)
What is hemostasis?
The stoppage of bleeding.
What is an anticoagulant?
Drug that interrupts the clotting cascade.
What is an antiplatelet?
Drug that decreases the formation of platelet plugs
What is a fibrinolytic?
Drug that acts directly on thrombi to break them down; also called thrombolytic.