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83 Cards in this Set

  • Front
  • Back
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integumentary system is comprised of?
epidermis & dermis
skin
four functions of integument
1. Protection
2. Excretion
3. maintenance
4. vitamin D3 synthesis
Thick skin has 5th layer of epidermal cells and is located
palms and balls of feet
5 layer of epidermis
1. Stratum
2. spinosum
3. Granulosum
4. lucidum
5. corneum
2 layers of dermis
1. papillary layer
2. recticulary layer
what level must be damaged before a scar is created?
dermis
the turn over rate of epidermis
21-24 days
epidermal ridges
extends into dermis in downward folds
dermal papilla
extend into epidermis in upward folds
sensible perspiration
loss by activity sweating
insensible presiration
loss without us seeing or feeling it
xerosis
excessively dry skin
three things that create skin color
1. carotene- orange yellow pigment
2. melanin- protects skin from harmful effects of sun
3. dermam circulation- RBC contains hemoglobin which transport oxygen
The A-B-C-D-E of malignancy classification
A. (asymmetry)- irregular shape
B. (border)- irregular indistinct
C. (color)- tan, brown, black, red, pink, white, blue
D. (diameter)- >5mm considered dangerous
E. (evolving)- the lesion is gradually changing
Vit. D3 is important to our health as it helps epidermal cells synthesize
cholecalciferol ( vitamin D3)
lines of cleavage (of tension)
expresses the parallel arrangement of collagen and elastic fiber bundles of the arranged to resist forces applied to the skin during normal movement
surgically significant
incision go parallel to lines to less gap and reduce scar
epidermis
is a vascular and it gets nutrition and performs gas exchange by diffusion from blood supply that exists in the dermis
5 types of skin sensation
1. touch
2. position sense
3. pain
4. temperature
5. contact to hair
the composition of the epidermis is stratified squamous epithelium the dermis ( mostly dense irregular CT) and hypodermis ( mostly areolar and adipose CT)
front if card only
sebaceous
holocrine (entire cell ruptures) glands associated with hair sebum lipid, oily, liquid secretion deposited into hair follicle
2 types if sweat glands
1. Apocrine sweat gland
2. merocrine (aka Eccrine) sweat gland

2-5 million with most on palms & soles

99% water + NaCl, etc
the 3 stages of integument healing
1. inflammatory
2. proliferative
3. Remodeling
first degree burn
only superficial epidermis involved (a sun burn)
second degree burn
entire epiermis +/- dermal involvement
- erytherna, blister, pain, swelling
-secondary structures not harmed
- heal In 1-2 weeks with possible scarring

third degree burn
full thickness (all of epidermis and dermis)
-maybe even into subcutaneous
-no pain as nerve destroyed
-often need skin graft to cover defect
- heal by scar
Rules of 9's quick way to estimate percentage of body burned
9% - head
9% - each arm
18% - each leg
18% - anterior trunk
18% - back
1% - genitals

if 80% of body is burned your survival rate is only 50%

life threatening dangers
1. fluid & water loss 5X normal
2. Provide nutrients to meet increased metabolic needs
jaundice
when the body unable to excrete bile yellow pigment accumulates in the body fluids and the skin takes on a yellowish tint
vitiligo

loss of metanocytes in certain regions of skin (light area)
rickets
lack vitamin D harms bone formation/maintenances (poor diet or lack of sunlight)
dermatits
general term for inflammation of the papillary layer seen infection, mechanical or chemical insult
turgor
indicates the degree of skin hydration
cerumen
ear wax
sepsis
A whole body inflammation caused by an infection
sebum
lipid, oily, liquid secretion deposited into hair follicle
actinic keratosis
scaley areas of sun damage seen in the aged and pale - not cancer but sometime turn into cancertreatment-freeze, mild acids
Basal cell carcinoma
cancer starts in S.Germinativum

-good prognosis If removed before metastasis

-95% of 5 year survival rate removed
squamous cell
accursev I n sun exposed sites

-95% - 5 year surval rate after excision
malignant melanoma
life threatening

- melancytes grow rapidly and metastasize through lymphatics

-if extensive locally before spreading has 99% survival rate at 5years with extensive metastasis only 14% survival rate
suture
between bone and skull
synchondrosis
between ribs and sternum when cartilage involved
synovial joint
surrounding by fibrous "articular cartilage" and the joint cavity is lined with a "synovial membrane
synovial joint componetsy
1. articular cartilage
2. synovial fluid
3. joint capsule
4. menicus
5. fat pad
6. ligament
7. tendon
8.brusae (bursitis)
the greater the range in joint the greater weakness and thus the greater likelihood for damage
front of card only
hinge
permits angular motion in one plane like a door hinge

ex. elbow, knee, ankle interphalangeal joint
ball and sockey
round bone fits into the cup of another bone allows circumduction an rotation

-ex. shoulder an hip joints
slipped disc
when the posterior longitudinal ligament weakens the nucleus puplposus pushes part way into the vertebral cancal
herniated disc
when the nucleus pulposus both migrates and the annulus fibrosis rubtures; protrusion into vertebral canal occurs


in both cases there could be spinal nerve compression
knee joint
A very complex hinge joint

- union of femur to tibia

-rounded distal aspect of femur rolls on superior surface of tibia

-allows flexion, limited extension and limited internal (when knew flexing) and external (when knee extending) rotation

menisci- 2 in each joint; called medial and lateral meniscus

Ligaments- 7 per knee
4 kinds of arthritis
1. osteoarthritis (OA)- characterized by spurring around joints

2. Rheumatoid Arthritis- decreased joint space & eroded cartilage

3. Gouty Arthritis- clinical presentation and later bone erosion and tophi

4. Septic Arthritis- due to organism infecting
treatments for Arthritis
1. Regular exercise
2. physical therapy
3. anti- inflammatory
4. more exotic drug ( gold, methyltrexate)
5. surgery to remove or replace joint
5 functions of bone
1. support
2. storage
3. blood cell production
4. protection
5. leverage
the total number of bones in the body
206
6 classifications of bone
1. long bones
2. flat bones
3. sutural bones
4. irregular bones
5. short bones
6. sesamoid bones
the name of the structures of long bone and what they mean
1. diaphysis- the shaft
2. epiphysis- expanse at each end
3. metaphysis- area between the two above
4. compact bone (aka cortical) dense; found in the diaphysis and thinly around metaphysis
5. medullary cavity- center of long bone containing marrow
6. spongy bones (aka concellous or trabecular) between compact bone; primarily in eiphyis strength from struts of dense bone
Bone is like all connective tissue in that it is comprised if cells (osteocytes,etc), protein fibers (collagen), and a matrix (primarily calcium salts)
front of card only
4 types of cells and function in maintaining bone
1. osteocytes- mature bone cells
- function is to maintain bone matrix and help in bone repair

2. osteoblast- makes new bones eventually will become osteocyte

3. osteoprogenitor cell- primitive cell that produce osteoblast / aid in bone repair

4. osteoclasts- breakdown bone
- resemble macrophages in appearance
compact bone the parts of the Haversion (osteon) unit to include
1. haversion canal
2. volkman canal
3. lacunea
4. canaliculi
5. lamellac
trabeculae
bone struts that oppose stress (visible on radiographs) this bone reduces weight
red bone marrow
makes blood cells
yellow bone marrow
stores fat
periosteum
the lining of all compact bone except at the joint / contains nerves and blood vessels
endosteum
- the lining of the medillary cavity

actively involved in bone repair, growth & remodeling
contains osteoblast, osteoprogenitor, and osteoclasts
enchonral
bone replacing cartilage
secondary growth center
forms at either end of long bone, bone replacing
appositional growth
growth at outer surface of bones

- how bone gets wider

- osteoblasts in periosteum create bone
primary growth center
forms in center of original cartilage
bone replacing cartilage
3 point of blood supply to the bone
1. nutrient arteries
2. metaphyseal vessels
3. periosteal vessels
bone Is well supplied with
nerves and lympathaties
remoldeling
there is constant recycling and renewal of organic and mineral components of bone matrix
turnover rate
young adults turn over bone at 20% per year. some bone turns over faster than other bone. the spongy bone of the femoral head might turnover 2-3 time per year
exercise
bone is deposited in response to mechanical stress
disue
can result in loss off 33% of bone Mass
bone is storage house for
calcium and phosphate
Vit. C, Vit. A, and Vit. D
necessary for healthy bone
calciriol
synthesized in kidney from Vitamin D3

need for GI tract to absorb calcium and phosphate, deficiency results in rickets
estrogen and androgens
at puberty these speed osteoblast activity to close epiphysis girl bone matures faster than boys as estrogen has greater effect than androgens
growth hormone
pituitary and thyroid glands involved stimulates bones growth until maturity
calcitonin
thyroid gland produces decreases calcium levels in body fluid by inhibit I ng osteocyte activity and increasing calcium loss at kidneys
parathyroid hormone
produced by parathyroid glands; increases calcium concentrations in body fluids by stimulating osteoclasts to break down bone and release calcium into blood stream
bone maladies
1. pituitary dwarfism
2. Giantism
3. Acromegaly
4. marfan syndrome
5. osteopenia
6. osteoporosis

levels increase more than 30%
- muscle in responsive

decreases more than 35%
-nerves to excited or death
Normal value of Ca+ plasma concentration
8.5-10.5 mg/dl
Fracture healing
-the endosteum eventually forms an internal callus while periosteum forms and external callus

New bone heals fracture excessively and must be remodeled back to normal shape

The main factors of fracture healing include sufficient blood supply, alignment of the bone fragments and stability of fragments to allow healing