Chapter 46

Front 1

Nucleoside nucleotide reverse transcriptase inhibitors

Back 1

First class of drugs approved by the FDA to treat HIV infection and eights prototype drug zidovudine ( AZT, ZDV, retrovir)

Front 2

zidovudine

Back 2

Epstein Barr Virus hepatitis B virus and HIV infection administer 1 hour before meals make sure the patient is on a low fat diet im injection should not be administered to patients receiving laboratory data should be obtained every 2 to 4 weeks

Front 3

Non nucleoside reverse transcriptase inhibitors

Back 3

Comprise the second class of drugs used to treat HIV infection affect only hiv-1 they do not inhibit reverse transcriptase and hiv2 they inhibit a specific site on the reverse transcriptase that is required to carry out the process of DNA synthesis prototype drug efavirenz (sustivia)

Front 4

efavirenz

Back 4

Hiv-1 infection inhibits HIV reverse transcriptase adverse effect Steven Johnson syndrome interacts with grapefruit juice benzodiazepine take once a day preferably at night for missed doses it is important that the patient take the drug as soon as remember unless it is time for the next dose take on empty stomach pregnancy category D drug

Hint 4

non nucleoside reverse transcriptase inhibitor

Front 5

Protease inhibitors

Back 5

The third major class of drugs used in treating HIV infection and AIDS represent the most potent anti-hiv drug prototype drug sanquinavir (Invirase)

Front 6

Saquinavir

Back 6

Treating HIV and infections in adults approve only in combination with 2 reverse transcriptase inhibitors contraindicated for children under 16 hepatic dysfunction dyslipidemia in diabetics fat distribution Buffalo Hump avoid grapefruit orange juice and garlic limit high fat and high cholesterol foods administer within 2 hours after eating a full meal administer ritonavir with each dose

Front 7

Integrase inhibitors

Back 7

Newest class of 88 art therapy approved for management of HIV disease block or inhibit the wholesale D&H producing netic material for new vs prototype rAategravir (Isentress)

Front 8

Raltegravir

Back 8

For HIV strains that are resistant to multiple antiretroviral regimen and experience it on going viral replication were receiving haarT no known contra-indications use cautiously with drugs that can cause muscle problems drug interactions many Haart medications rifampin proton pump inhibitors you given with or without food ensuring not use as monotherapy

Hint 8

Integrase inhibitor

Front 9

Entry inhibitors

Back 9

Known as fusion inhibitors inhibit the HIV virus from phone into frozen with internet human cell prototype drug Enfuvirtide (Fuzeon)

Front 10

enfuvirtide

Back 10

Managing HIV infection in patients who have experienced treatment failure administer subq drug drug interactions have not been identified pregnant category B bring to room temperature before injection used 2 dose vial second injection refrigerate

Hint 10

Entry inhibitor