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4 Cards in this Set
- Front
- Back
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Quinolones/fluoroquinolones
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Like cephalosporins are divided into generations 1st generation quinolones are use only to treat a uncomplicated uti second generation fluoroquinolones have increased gram negative in systemic activity third generation fluoroquinolones have extended activated gram positive pathogens fourth generation fluoroquinolones have extended activity against pseudomonas prototype drug ciproflaxin (cipro)
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ciprofloxacin
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Active against a Rubik gram negative organisms inhibits DNA gyrase many potential drug drug interactions due to metabolism monitor for yeast infection the most clinical importance adverse reaction is joint disease arthropathy
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Cyclic lipopeptides
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Ability to retain potency against anti biotic resistant gram-positive bacteria daptomycin (Cubicin)
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daptomycin
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Used to manage complicated skin infections use large needle renal insufficiency no clinically important drug drug interactions have been identified pregnancy category B drug caution in elderly before administration and visually inspect for particulate matter and discoloration administer with 0.9 percent sodium chloride or lactic Ringer solution
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