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129 Cards in this Set

  • Front
  • Back
The term poisoning usually refers to ____, while the term overdose refers to ____,
Poisoning- Nonpharmacological substances
Overdose-pharmacological substances
p1350
Cyanide
Found in rodenticides, silver polish, fruit pits, fires, burning plastic bags, silks, synthetic carpets. (extremely fast acting)
The American Assoc. of Poison Control Centers estimates more than ___ million poisonings occur annually
4 million
p1351
Cyanide S/S
Burning sensationin mouth and throat
headache, cofusion, combative, HTN, Tahcy followed by Hypotension and dysrythmias, seizures, coma, pulmonary edema
___% of all ER visits and EMS response involve toxic exposures
10%
p1351
Cyanide Tx:
PPE
remove pt from area
initiate supportive care
cyanide kit
____% of accidental poisonings occur in children under 6 years old
70%
p1351
Cyanide kit
It converts some hemoglobin into methemoglobin which cyanide binds to, then it's broken down to thiocyanate that is excreted renally.
A child who has experienced an accidental ingestion has a __% chance of another, similar ingestion w/in 1 year
25%
p1351
CO poisoning
Oderless and tasteless gas from the product of incomplete combustion. Causes effective hypoxia
__% of all attempted suicides involve drug overdose
80%
p1351
CO poisoning S/S
Early Signs are simular to the flu
Headache, n/v , confusion/AMS, tachy breathing
More than half of all poisonings occur in children ages 1-5, accounting for __% hospital admissions and __% fatalities
10%
5%
p1351
CO poisoning Tx
Definitive tx is hyperbarric chamber for high level of O2 therepy
PPE, remove pt, vent area, supportive care, high flow O2
Adult poisonings account for __% hospital admissions and ___% fatalities
90%
95%
p1351
Cardiac Med
Overdoses of these drugs are usually errors in dosages
Name the 4 types of toxic exposure
*Ingestion
*Inhalation
*Surface absorption
*Injection
p1352
Cardiac Med S/S
N/V, headache, dizziness, confusion, profound hypotension, dysrythmias, heart blocks, bronchospasm, pulmonary edema
Name the most common route of entry for toxic exposure
Ingestion
p1352
Cardiac Med Tx
Standard toxocology assessment
Severe bradycardia may not respond to atropine
ABC's
Contact med control for assist.
___ of a poison results in rapid absorption of the toxic agent through the alveolar-capillary membrane in the lungs.
Inhalation
p1352
Caustic Substances (acids)
Ph less than 2 found in plumbing liquids and bathroom cleaners produces immediate severe pain due to tissue coagulation and necrosis. Contact injury will produce Eschar which will act like a shield and prevent further damage. Ingestion will cause local burns aroun the mouth and throat the stomach lining will be injured
This type of exosure occurs with contact of poisonous plants and toxic chemicals like organophosphates
Surface absorption
p1352
Caustic Substances (alkalines)
Ph greater than 12.5 can be solid or liquid form like drano or liquid plumber. These agents cause injury by inducing liquefafcation necrosis, pain is delayed which allows for longer tissue contact and deeper tissue injury before exposure is recognized. Solid agents stick to the oropharynx or esophagus causing perferations, bleeding inflammation of the central chest structures. 2-3 days of exposure there is a loss of protective mucosal tissue.
This type of exposure results in both immediate and delayed effects, and is often entered under the skin, into the muscle, or into the blood vessel
Injection
p1353
Caustic Substances S/S
Facial burns
pain in lips, tongue, thraot, gums,
drooling
trouble swallowing, hoarsness, stridor, SOB, vomiting, shock
Standard Toxicological Emergency Procedures
*Recognize a poisoning promptly
*Assess the pt thoroughly to identify the toxin and measures required to control it
*Initiate standard treatment procedures (protect rescuer, remove pt from environment, ABC's, Decon, Administer antidote is exists)
p1353
Caustic Substances Tx
PPE
Toxocology emergency standards
Airway managment ( might have to cric)
Rapid transport
It is important to find out not only what the toxin the pt was exposed to but _____
when the exposure took place
p1353
Hydrofluoric Acid
Extremely toxic can be lethal despite the apperence of only moderate burns, it penetrates into tissues and is inactivated only when it contacts cations like calcium. It settles in the tissues as salt and removes calcium from the cells causing a disruption of cell function, even causes bone destruction, by pulling calcium from the bones. (death has been reported in exposures of less than 2.5 % BSA)
Name the 3 principles of decontamination
*Reduce intake of toxin(remove from environment)
*Reduce absorption of toxin once in the body(syrup of ipecac, gastric lavage, activated charcoal)
*Enhance elimination of toxin(increases gastric motility, whole bowel irrigation)
p1354
Hydrofluoric Acid S/S
Burning at site of contact
Trouble breathing
Confusion
Palpatations
Muscle Cramps
True or False
There are many antidotes available and will usually be 100% effective.
False
There are not many antidotes and are rarely 100% effective
p1355
Hydroflouric Acid Tx
PPE
Supportive care
Remove exposed clothing
Irrigate
Immerse limbs in iced water and Mag Sulfate
Transport immediatly
If you leave a suicidal pt who claims to be "just kidding", you could later be charged with___
Patient abandonment
p1355
Hydrocarbons
Organic compounds, common names kerosene, naptha, turpentine, mineral oil, chloroform, paint , glue, lubricants, solvents. Routes include ingestion, inhalation, surface absorbtion
The most common route of poisoning you will encounter in prehospital care is
Ingestion
p1356
Hydrocarbons S/S
Burns due to local contact, wheezing, dyspnea, hypoxia, headache, dizziness, slurred speech, ataxia, dulled reflexes, foot and wrist drop with numbness and tingling, dysrythias
For ingested toxins, begin your history by trying to find out the __ of toxin ingested, ___ of the toxin, ___ elapsed since ingestion.
Type
Quantity
Time
p1355
Hydrocarbons tx
Few poisonings are serious. If you know the exact chemical and pt is asymptomatic med control mayy aloow a refusal. If symptomatic supportive care utlize med control for assist. Activated Charcol will not bind with toxin. Gastric Lavage may be used
The physical examination of ingested toxins has 2 purposes
1-to provide physical evidence of intoxication
2-to find any underlying illnesses that may account for the pts symptoms
p1356
Tricyclic Antidepressents
Used for chronic pain or migranes, not so much for depression anymore. More deaths are from overdoses. Common agents: Elavil, Amoxopine, Doxepin, Imipramine, Nortriptyline
Name the 6 different pt features that you want to pay attention to during your physical exam of ingested toxins
1-skin
2-eyes
3-mouth
4-chest
5-circulation
6-abdomen
p1356
Tricyclic Antidepressents S/S
Dry mouth, blurred vision, urinary retention, constipation

LATE SIGNS: Confusion, Hyperthermia, Resp. depression, Seizures, Tachy with Hypotension, Dysrythmias
Ingested Poisons
Management
*Top priority- Maintain ABC's
*Major objective- prevent aspiration
RSI may be required, high-flow O2, IV TKO, cardiac monitor,
*DO NOT GIVE COMA COCKTAIL (D50, naloxone, thiamine), instead treat what you find
p1357
Tricyclic Antidepressents Tx
Immediate toxicology Standard
Cardiac monitoring, if suspected overdose with benzo's do not use flumazanil, Use Bicarb, contact med control
Inhaled toxic substances produce signs and symptoms primarily in the _____
Respiratory system
p1358
MAOI
Monomine Oxidase Inhibitors treat depression or obsessive compulsive disorder. These drugs inhibit the breakdown of nerotransmitters such as norepi and dopemine, Symptoms may not appear for up to 6 hrs
Aerosol Inhalation
Signs and Symptoms
*Central Nervous System-dizziness, headache, confusion, seizures, hallucinations, coma
*Respiratory-tachypnea, cough, hoarsness, stridor, dyspnea, retractions, wheezing
*Cardiac- dysrhythmias
p1358
MAOI S/S
Headache, aggitation, restless, tremor, nausea, palpatations, tachycardia, severe hypertention, hyperthermia, eventualy bradycardia, hypotension, coma, death
Inhalation
Management
*safely remove the pt from the poisonous environment
*perform the primary assessment, history, and physical exam
*initiate supportive measures
*contact poison control center and medical director according to protocols
p1358
MAOI Tx
No atidote exist
standard toxocolgy standard
seizure control if needed, if vasopressors are needed use norepi
Signs and symptoms of absorbed poisons can vary depending on ____
toxin involved
p1358
Cithium
Treatment for bipolar disorders. Has a narrow theraputic index (don't take much to kill you)
When you suspect absorption of a toxin follow these steps
*Safely remove the pt from the environment
* wear protective clothing
* use appropriate respiratory protection
* remove pts contaminated clothing
* perform assessment, history, physical exam
*initiate supportive measures
* contact poison control and medical director according to protocols
Cithium S/S
Thirst, dry mouth, tremors, muscle twitching, confusion, stupor, seizures, coma, N/V, diarrhea, bradycardia, dysrhythmia
Cithium Tx
Supportive measures, alkalinizing the urine w/ bicarb and mannitol may increase elimination,of lithium,severe cases reguire hemodialysis
Cyanide
Found in rodenticides, silver polish, fruit pits, fires, burning plastic bags, silks, synthetic carpets. (extremely fast acting)
Cyanide S/S
Burning sensationin mouth and throat
headache, cofusion, combative, HTN, Tahcy followed by Hypotension and dysrythmias, seizures, coma, pulmonary edema
Cyanide Tx:
PPE
remove pt from area
initiate supportive care
cyanide kit
Cyanide kit
It converts some hemoglobin into methemoglobin which cyanide binds to, then it's broken down to thiocyanate that is excreted renally.
CO poisoning
Oderless and tasteless gas from the product of incomplete combustion. Causes effective hypoxia
CO poisoning S/S
Early Signs are simular to the flu
Headache, n/v , confusion/AMS, tachy breathing
CO poisoning Tx
Definitive tx is hyperbarric chamber for high level of O2 therepy
PPE, remove pt, vent area, supportive care, high flow O2
Cardiac Med
Overdoses of these drugs are usually errors in dosages
Cardiac Med S/S
N/V, headache, dizziness, confusion, profound hypotension, dysrythmias, heart blocks, bronchospasm, pulmonary edema
Cardiac Med Tx
Standard toxocology assessment
Severe bradycardia may not respond to atropine
ABC's
Contact med control for assist.
Caustic Substances (acids)
Ph less than 2 found in plumbing liquids and bathroom cleaners produces immediate severe pain due to tissue coagulation and necrosis. Contact injury will produce Eschar which will act like a shield and prevent further damage. Ingestion will cause local burns aroun the mouth and throat the stomach lining will be injured
Caustic Substances (alkalines)
Ph greater than 12.5 can be solid or liquid form like drano or liquid plumber. These agents cause injury by inducing liquefafcation necrosis, pain is delayed which allows for longer tissue contact and deeper tissue injury before exposure is recognized. Solid agents stick to the oropharynx or esophagus causing perferations, bleeding inflammation of the central chest structures. 2-3 days of exposure there is a loss of protective mucosal tissue.
Caustic Substances S/S
Facial burns
pain in lips, tongue, thraot, gums,
drooling
trouble swallowing, hoarsness, stridor, SOB, vomiting, shock
Caustic Substances Tx
PPE
Toxocology emergency standards
Airway managment ( might have to cric)
Rapid transport
Hydrofluoric Acid
Extremely toxic can be lethal despite the apperence of only moderate burns, it penetrates into tissues and is inactivated only when it contacts cations like calcium. It settles in the tissues as salt and removes calcium from the cells causing a disruption of cell function, even causes bone destruction, by pulling calcium from the bones. (death has been reported in exposures of less than 2.5 % BSA)
Hydrofluoric Acid S/S
Burning at site of contact
Trouble breathing
Confusion
Palpatations
Muscle Cramps
Hydroflouric Acid Tx
PPE
Supportive care
Remove exposed clothing
Irrigate
Immerse limbs in iced water and Mag Sulfate
Transport immediatly
Hydrocarbons
Organic compounds, common names kerosene, naptha, turpentine, mineral oil, chloroform, paint , glue, lubricants, solvents. Routes include ingestion, inhalation, surface absorbtion
Hydrocarbons S/S
Burns due to local contact, wheezing, dyspnea, hypoxia, headache, dizziness, slurred speech, ataxia, dulled reflexes, foot and wrist drop with numbness and tingling, dysrythias
Hydrocarbons tx
Few poisonings are serious. If you know the exact chemical and pt is asymptomatic med control mayy aloow a refusal. If symptomatic supportive care utlize med control for assist. Activated Charcol will not bind with toxin. Gastric Lavage may be used
Tricyclic Antidepressents
Used for chronic pain or migranes, not so much for depression anymore. More deaths are from overdoses. Common agents: Elavil, Amoxopine, Doxepin, Imipramine, Nortriptyline
Tricyclic Antidepressents S/S
Dry mouth, blurred vision, urinary retention, constipation

LATE SIGNS: Confusion, Hyperthermia, Resp. depression, Seizures, Tachy with Hypotension, Dysrythmias
Tricyclic Antidepressents Tx
Immediate toxicology Standard
Cardiac monitoring, if suspected overdose with benzo's do not use flumazanil, Use Bicarb, contact med control
MAOI
Monomine Oxidase Inhibitors treat depression or obsessive compulsive disorder. These drugs inhibit the breakdown of nerotransmitters such as norepi and dopemine, Symptoms may not appear for up to 6 hrs
MAOI S/S
Headache, aggitation, restless, tremor, nausea, palpatations, tachycardia, severe hypertention, hyperthermia, eventualy bradycardia, hypotension, coma, death
MAOI Tx
No atidote exist
standard toxocolgy standard
seizure control if needed, if vasopressors are needed use norepi
Cithium
Treatment for bipolar disorders. Has a narrow theraputic index (don't take much to kill you)
Cithium S/S
Thirst, dry mouth, tremors, muscle twitching, confusion, stupor, seizures, coma, N/V, diarrhea, bradycardia, dysrhythmia
Cithium Tx
Supportive measures, alkalinizing the urine w/ bicarb and mannitol may increase elimination,of lithium,severe cases reguire hemodialysis
The most common source of injected poisons is the _______________.
Animal kingdom
P1372
__________ includes wasps, bees, hornets and ants.
Hymenoptera
P1373
Wasps, yellow jackets, hornets and fire ants ________ repeatedly until removal from contact.
Sting
P1373
In most cases of insect bite, _________ treatment is all that is necessary.
Local
P1373
Management for Hymenoptera stings?
Wash area
Gently remove stinger
Apply cool compress
Observe for and tx reactions/anaphylaxis
P1373
________ can be immobilized and killed with wettiing agents (surfactants) including comercial dishwashing soaps.
AHBs (Africanized honeybees)
P1373
____________ spider bites are usually painless.
Brown recluse
P1374
A brown recluse bite initially presents with a small erythematous macule surrounded by a ________ ring forms at the site. this usually appears within a __________ of the bite.
White
Few minutes
P1374
Management of a brown recluse bite:
Supportive care
ER tx of antihistamines.
No antivenin
P1374
The venom of the legendary _____________ is very potent, causing exessive neurotransmitter release at the ____________ junctions.
Black widow
Synaptic
P1374
S/S of a black widow spider bites start as ___________ localized pain, redness and swelling.
Immediate
P1375
(Black widow bite)
Progressive muscle spasms of all ________ muscle groups can occur and are usually associated with _______ pain.
Large
Severe
P1375
Management of black widow bite:
Supportive care
Dr order - Diazepam (2.5-10mg IV or Calcium Gluconate (0.1-0.2/kg of 10% solution IV for severe spasms
Watch for HNT
Antivenin is available
P1375
All scorpions can sting, causing localized pain, but only one, the __________, has caused fatalities.
Bark scorpion
P1376
The bark scorpion's venom acts on the __________ system.
Nervous
P1376
Management of the bark scorpoin sting.
Apply a VCB above the wound site no tighter than a watchband to occlude _________ flow only.
Avoid use of ___________, which may increase toxicity and poteniate the venom's effect on airway control.
Lymphatic
Analgesics
P1376
Common ____________ are cottonmouths (water moccasins), rattlesnakes and copperheads.
Pit vipers
P1376
Coral snake mnemonic:
red touch yellow, kill a fellow. red on black, venom lack.
P1377
Pit viper venom contains __________ enzymes that are capable of destroying proteins and most other tissue components.
Hydrolytic
P1377
A severe pit viper bite can result in death from shock within ________.
30 min
P1377
In treating a person who has been bitten by a pit viper, the primary goal is to ______________ of the venom.
Slow absorption
P1377
About ___% of all rattlesnake bites are "dry" and no venom is injected.
25%
P1377
Management of pit viper bites:
Keep pt supine
Immobilize the limb
Maintain the extremity in a neutral position.
Do not apply VCB
Do not apply cold pack
P1378
The classic, severe coral snake bite will result in ___________ and ___________ muscle paralyisis.
Respiratory
Skeletal
P1378
After the bite of a coral snake, there may be no local manifestations or even any systemic effects for as long as _______ hours.
12-24 hours
P1379
Management of coral snake bites:
Wash wound with copious amounts of water
Apply compression bandage
Keep extremity at level of heart
Immobilize the limb
Do not apply ice pack
P1379
All venoms of marine animals contain substaces that produce pain out of _________ to the size of the injury.
Proportion
P1379
Marine animal poisonous toxins are unstable and ________ sensitive. Heat will relieve pain and ______________ the venom.
Heat
Inactivate
P1379
Management of marine animal injections:
Apply VCB to occlude lymphatic flow only.
Apply heat or hot water (110-113F)
Inactivate or remove any stingers
P1380
Use of pharmacological substance for reason other than medical reason.
Substance abuse
Physiological or psychological dependance on substance.
addiction
Need to increase dose of drug to get original desired effect.
tolerance
Pt reacts severely when deprived of substance.
withdrawl
Crack head stats:
28 mill used drugs at least once
14.5 mill use regularly
20 mill tried cocaine
860,000 use coc weekly
11.6 mill use weed reg
770,000 use hallucinogens reg
2.5 mill have used heroin
Poisoning from excess of substance.
drug overdose
Drugs and supportive TX:
Alcohol - thiamine and D50

Cocaine - Diazepam (seizure activity) NO BETA BLOCKERS

Narcotics/Opiates - Naloxone

Amphetamines - Diazepam and haloperidol (hyperactivity)

Hallucinogens - Diazepam and haloperidol (hyperactivity)

Benzodiazepines - Flumazenil

Barbituates - Diuretics and alkalies
___ % of Americans have an alcoholic drink a year.

___ % of all deaths in American related to alcohol.
75%

5%
Alcohol completely absorbed by intestinal tract between __ and ___ minutes.
30 - 120
Alcohol leads to the stopping of natural vasopressin in the body which is responsible for conservation of body fluids. This is why when you drink you:
PISS LIKE A RACEHOARSE
Chronic drinking leads to:
Poor nutrition
Hepatitis
Cirrhosis
Loss of peripheral sensation
Hypoglycemia
Withdrawal symptoms:
Last 5 - 7 days
seizures

Delirium Tremens (DT)
DTs
Seen 48 - 72 hours after last drink
Hallucinates
Seizures
Tremors
TX of alcohol emergency:
IV
NS
25 g D50 is hypoglycemic
100 mg thiamine