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63 Cards in this Set

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  • Back
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All cells composed of which 4 atoms

C, H, N, O

What makes up the plasma membrane

Phospholipid bilayer, mostly unsaturated



Glycolipid, sugar groups



Cholesterol, keeps membrane fluid consistent



Lipid rafts, platforms for cell signaling



Glycocalyx, cell surface area

Transmembrane Protein

Integral protein that goes from extracellular enviro to intracellular enviro

Integral proteins

Involved in transport



Deeply imbedded membrane

Peripheral protein involved in:

Support, enzymatic reactions, and mechanical functions

Microvilli

Increases surface area

Name the membrane junctions:

Tight junction, Desmosomes, and Gap junction

Tight Junction

Fusion of integral protein, impermeable



Found in skin and small intestines

Desmosomes

Anchoring junctions, attached by protein plaques linked with linker proteins



Found in tissues subjected to mechanical stress, skin

Gap Junction

Communication of ions and small molecules

Membrane Transport

Selectively permeable membrane



Can be active of passive

Passive Transport, list some examples:

No E needed



Diffusion--Simple Diffusion, Facilitated Diffusion; Osmosis

Diffusion

Movement if solute from high to low concentration

Simple Diffusion: definition, which substances, examples

Diffusion directly through the lipid bilayer



Only nonpolar and lipid soluble substances



Example. Oxygen, carbon dioxide, fat-soluble vitamins, alcohol

Facilitated Diffusion - Carrier Mediated: how, which substances, which carriers

Specific proteins attaches/bind to carrier substance and is transported into the cell



Larger and polar molecules



Transmembrane proteins

Facilitated Diffusion - Channel Mediated: definition and which substances thru which channels

Specific molecules based on size and charge that goes thru the leakage channel (always open) or gated channel (controlled by signals)



Mostly ions

Osmosis

Diffusion of water from hight to low concentration

Where does water move?

Water moves to where the "stuff" are

Tonicity

Ability of a solution to change shape of the cell by changing water volume

Hypotonic

More concentrate inside the cell



Lysis, cell bursts

Hippo likes?

Hypertonic

More concentration outside of cell so water leaves the cell



Crenation - shriveled

Isotonic

Equal numbers of the concentration in and outside of the cell

Active Transport, name some examples

Requires E input, ATP



Primary, Secondary, and Vesicular

Primary Active Transport

Solute travels against gradient



Direct use of ATP



Sodium Potassium Pump

Sodium Potassium Pump

3 Na+ out, 2 K+ in



More K inside, More Na outside



ATP used

Secondary Active Transport

Displays specificity



Indirect use of ATP



As one substance travels down its gradient, it "pulls" another substance along

Vesicular Transport

No proteins, moved by vesicles



Larger particles



Powered by ATP

Endocytosis, examples?

Substances moved into cell



Phagocytosis, Pinocytosis, Receptor mediated Endocytosis

Exocytosis, how? Example?

Substances move out of cell



Fusion with plasma membrane by vesicles and released to the outside



Example. Neurotransmitter

Phagocytosis : specificity? Definition? Example?

Maybe specific, large particles



"engulfs/eats" material to form phagosome



Combines lysosome to digest material



Example. Macrophages

Pinocytosis : specificity? Definition? Example?

Nonspecific, small particles



"dirt", sampling of extracellular fluid



Example. Intestinal cell absorbing nutrients

Receptor mediated Endocytosis : specificity? Definition? Example?

Specific



Receptors outside of membrane



Example. Insulin, LDL

What are the charges of the plasma membrane?

Inside (-), outside (+)



Due to chemical and electrical gradient



Proteins line the inside of the membrane unable to leave

Inside? Outside? Where do proteins line?

K is the chemical formula for?

Potassium

P is the chemical formula for?

Phosphorus

What is the chemical and electrical gradient?

Electrical: More K+ inside of cell so it attracts (-) charge



Chemical: pulls it out

Potassium pull...

What is RMP?

When concentration and electrical gradient equalizes

Resting membrane potential

G-Link Receptors (steps)

1. First chemical messenger binds to membrane receptor


2. In turn sets off the second messenger



G protein acts as a relay messenger

Cillia

Cellular extensions found on the apical side of a tissue

Flagella

Cellular extention involved in movement

Only found in sperm

Nucleus: overall function, contains what, what happens here

Control center



Contains genetic material



Site of DNA Synthesis

Cell that has more than one cell

Mulinucleate

Liver cells, osteoclasts

Cell with no nucleus

Anucleate

Red blood cells

Nucleoli

Site of ribosomal Synthesis and assembly

Chromatin

DNA and histones

Histones

Type of DNA ; protein that organizes the DNA and regulates gene expression

Chromosomes

Condensed chromatin formed during cell division

Name the steps in Cell Life Cycle

Interphase : G1, S, G2


Mitotic Phase : Pro, Meta, Ana, Telo, Cytokinesis

Describe Interphase

First phase in the cell's life cycle



1. G1, growth


2. S, DNA Synthesis occurs


3. G2, growth and checkpoint for cell division

3 steps

Describe Mitotic Phase

Division of the nucleus



1. Pro: chromatin condenses, Mitotic spindles form and attach to chromosomes, nucleolus disappears, nuclear envelope fragments



2. Meta: chromosomes line up at the center



3. Ana: sister chromatin pulled apart to opposite ends, cell lengthens



4. Telo and Cytokenesis: chromosomes uncoil, nuclear envelope and nucleoli reappear, spindles disappear, cleavage furrow forms for division of cytoplasm

P. M. A. T.

Semiconservative DNA replication

Each parent strand serves as a template for the new DNA molecule

What is the term that describes DNA replication? Parent-daughter strand

Semiconservative

What is G0 (zero) phase?

When a cell reaches maturity and doesn't divide anymore

Introns

Contained in genes, they are the noncoding DNA sequences

In genes

Exons

Code for Protein Synthesis in genes

In genes

tRNA

RNA that brings the correct AA to the growing polypeptide chain

rRNA

Site of protein Synthesis

mRNA

Serves as a transcript, makes copies

Describe Protein Synthesis

Replication, Transcription, Translation



Replication : DNA copies itself



Transcription : information in DNA copied to mRNA



Translation : mRNA sequence is made into protein

3 steps

Transcribe this DNA sequence : cat, gag, tag, tac

GUA, CUC, AUC, AUG

What are the steps of Translation of Protein Synthesis?

1. Initiation : tRNA goes to P site, AUG starts the process


2. Elongation : codon recognized, tRNA goes to A site; peptide bond formed from protein in P site to AA in A site


3. Termination : special base sequence signals end of process; ribosome disassemble, mRNA released

Transcription, what are the sites?

P site, initiation starts with AUG, methionine



A site, new tRNA sits with AA and bonds with the polypeptide



E site, tRNA exits the ribosome

What are the stop colons?

UAA, UAG, UGA