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29 Cards in this Set
- Front
- Back
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1. During fetal life, the synthesized hemoglobin is composed of two alpha and two beta chains. |
False
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2. Although a frequent problem, ABO incompatibility seldom results in significant disease. |
True
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3. Sequestration crisis is a serious complication of sickle cell disease that is unique to childhood. |
True
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4. Rh incompatibility is a problem only for an Rh-positive woman bearing an Rh-negative fetus during a second pregnancy. |
False
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5. Because hemostasis in the newborn is chiefly attained through the extrinsic pathway, serious bleeding in the newborn period usually is not a problem in hemophiliacs. |
True
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6. ITP is a genetically transmitted disease. |
False
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7. Leukemias are multifactorial diseases, with genetic disposition, environment, and bacterial infections playing a role in their etiologies. |
False
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8. Which is the most common blood disorder of infancy and childhood? a. iron deficiency anemia b. pernicious anemia c. folate deficiency anemia d. sideroblastic anemia |
a. iron deficiency anemia
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9. Maternal-fetal blood incompatibility may exist in which condition? a. Rh-positive mother, Rh-negative fetus b. Rh-negative mother, Rh-positive fetus c. Rh-negative father, Rh-positive mother d. Rh-negative father, Rh-positive mother |
b. Rh-negative mother, Rh-positive fetus
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10. Beta-thalassemia is: a. common among Italians. b. an X-linked recessive disorder. c. an autosomal recessive disorder. d. Both a and b are correct. e. Both a and c are correct. |
e. Both a and c are correct.
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11. Which statement is correct? a. Sickle cell disease is an autosomal dominant disorder. b. Sickle cell disease is an X-linked recessive disorder. c. Sickle cell disease is an X-linked dominant disorder. d. Sickle cell disease is an autosomal recessive disorder. |
d. Sickle cell disease is an autosomal recessive disorder. |
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12. ITP involves antibodies against: a. neutrophils. b. eosinophils. c. platelets. d. basophils. |
c. platelets.
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13. Which are factors associated with iron deficiency anemia? a. rapid growth b. low socioeconomic status c. cow’s milk for infants d. Both a and c are correct. e. a, b, and c are correct. |
e. a, b, and c are correct.
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14. What is the most likely cause of ITP? a. stress and fatigue b. genetic predisposition c. prolonged occult bleeding d. viral sensitization e. Both b and c are correct. |
d. viral sensitization
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15. Hodgkin lymphoma has: a. extensive extranodal involvement. b. rare extranodal involvement. c. painless cervical lymphadenopathy. d. Both a and c are correct. e. Both b and c are correct. |
e. Both b and c are correct.
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16. In sickle cell disease, vasoocclusive crisis is the result of: a. damage to platelets caused by IgG. b. “plugging” of microcirculation by “stiff” sickled erythrocytes. c. ingestion of sulfa drugs. d. sequestration of large numbers of erythrocytes in the spleen. |
b. “plugging” of microcirculation by “stiff” sickled erythrocytes. |
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17. Which factor may play a part in the development of childhood leukemia? a. genetic predisposition b. environmental factors c. viral infections d. radiation e. All of the above are correct. |
e. All of the above are correct.
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18. Which statement is true about acute lymphocytic leukemia? a. It is the most common childhood leukemia. b. It usually occurs between 2 and 6 years of age. c. It is uniformly fatal. d. It is easily predicted through genetic testing. e. Both a and b are correct. |
e. Both a and b are correct.
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19. Leukocyte counts approaching 100,000/mm3 |
a. leukemia |
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20. Low platelet counts |
b. ITP |
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21. Lack of coagulation factors VIII, IX, and XI |
e. hemophilia |
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22. May manifest early as symmetric, painful swelling of hands and feet |
c. sickle cell disease |
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23. May cause severe hemolysis in the newborn period |
d. Rh incompatibility |
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24. May result in aplastic crises |
c. sickle cell disease |
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25. May result in fetal death |
d. Rh incompatibility |
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Hemophilia A |
Factor VIII deficiency, inherited as a X-linked recessive disorder |
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Hemophilia B (Christmas disease) |
Factor IX deficiency, inherited as a X-linked recessive disorder (less severe than hemophilia A) |
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Hemophilia C |
Factor XI deficiency, inherited as an autosomal recessive disease (less severe than either A or B) |
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von Willebrand disease |
Factor VIII deficiency, inherited as an autosomal dominant disease |
