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42 Cards in this Set

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Interstitial Fluid

Found between cells or in tissues

One type of extracellular compartment. Examples: lymph, cerebrospinal Fluid, GI secretions.

Intravascular Fluid

The plasma within the cells

Other type of extracellular compartment. Contains serum, protein, and other necessary substances.

Glomerular Filtration Rate

Nephrons filter blood at 125 mL/minute, about 180 L/day.

Adenosine triphosphate (ATP)

Chemical that supplies energy to perform active transport.

Produced in the mitochondria of cells.

Passive Transport

Process that moves substances through the cell membrane. 3 types: Diffusion, Osmosis, and Filtration.

Diffusion

Natural tendency of a substance to move from an area of higher concentration to one of lower concentration.

Results in an equal distribution of solutes

Osmosis

Movement of water across a semipermeable membrane, from an area of lower concentration to an area of higher concentration.

2 different solutions are separated by a membrane through which they cannot pass.

Hypertonic Solutions

Solution that pulls fluid from cells.

Isotonic Solutions

the body's blood volume w/o causing a fluid shift from one compartment to another.

Hypotonic Solutions

Solutions that move into cells, causing them to enlarge.

Hydrostatic Pressure

Force of fluid pressing outward on a vessel wall.

Active Transport

Process of moving molecules, against pressure, through a membrane using carriers and energy from the cell.

The carriers used are also known as pumps.

Electrolyte

Substance that develops an electric charge when it dissolves in water.

Ions

Electrically charged particle.

Cations

Posititively charged ions.

Anions

Negatively charged ions.

Milliequivalent (mEq)

A measure of the chemical activity of an ion.

Sodium

The most abundant electrolyte in the body. Major extracellular electrolyte. Helps regulate the contractility of muscles. Helps maintain neuromuscular irritability to improve nerve impulse conduction. Source of intake is mainly the diet.

Normal blood level is 135 - 145 mEq/L.

Hyponatremia

Condition that occurs after vomiting, diarrhea, or an excessive intake of water. The body's attempt to compensate by decreasing water excretion. Water is pulled into the cells, which causes them to be a edematous. As fluid moves into the cells, potassium is shifted out; therefore, the patient is likely have potassium inbalance as well.

Hypo: low


Hyponatremia occurs when the blood sodium level is less than 135 mEq/L.

Hypernatremia

Condition that occurs when the concentration of sodium is greater than normal. Caused by an excess of sodium or decrease in body water. Causes fluid to shift from the cells to the interstitial spaces, which results in cellular dehydration and an interruption in the cellular processes.

Hyper: high


Hypernatremia occurs when the blood sodium level is greater than 145 mEq/L.

Potassium

Electrolyte found primarily in the intracellular fluid and is the major intracellular cation. Main function of this electrolyte is the regulation of water and electrolyte content within the cell. Also promotes transmission of nerve impulses and also skeletal muscle function. Assists in the cellular metabolism of carbohydrates and proteins and helps control the hydrogen concentration. When this electrolyte moves out of the cell, sodium and hydrogen ions move in. This results in the regulation of acid-base balance.

Normal blood serum level is 3.5 - 5.0 mEq/L.

Hypokalemia

Condition where most common cause is renal excretion. The kidneys do not conserve and excrete it even when the body needs this elecrolyte. Intestinal fluids contain large amounts of potassium semicolon therefore, with excessive GI losses from suctioning these levels tend to become depleted.

Hypo: low


Occurs when blood potassium level is less than 3.5 mEq/L.

Hyperkalemia

Condition where the most common cause is renal disease in which this electrolyte is not excreted adequately. If kidney output is also reduced, the result is an elevation in the electrolyte's level.

Occurs when the blood serum potassium level is greater than 5 mEq/L.

Chloride

An extracellular anion that is really present alone. Usually bound to other ions such as sodium or potassium. Necessary for the formation of hydrochloric acid in gastric secretions. Necessary in the regulation of the osmotic pressure between the body's fluid compartments. Also assists in the regulation of acid-base balance. The main route of excretion for this electrolyte is through the kidneys.

Normal blood level is 96 - 106 mEq/L.

Hypochloremia

Condition usually associated with sodium loss. Vomiting, diarrhea, gastric suctioning, and acute infections all cause a loss of both sodium and this electrolyte.

Occurs when chloride levels fall below 96 mEq/L.

Hyperchloremia

Condition that occurs when bicarbonate levels fall and metabolic acidosis occurs. The the increase of this electrolytes Indians represent an attempt to compensate and maintain equal numbers with caitians in the body fluid.

Occurs when chloride levels in the blood exceed 106 mEq/L.

Calcium

A positively charged ion found mainly in the bones and teeth. Remains essentially inactive there until the levels in the blood fall. At that time this is released from the bones in an attempt to raise the blood level.

Normal blood levels should be 4.5 - 5.6 mEq/L.

Hypocalcemia

Condition that can be caused by chronic renal failure, pancreatic disease and alkalosis.

Occurs when blood levels fall below 4.5 mEq/L.

Hypercalcemia

Condition that may occur when is electrolytes stored in the bone enter circulation in excess.

Occurs when blood calcium level exceeds 5.6 mEq/L.

Phosphorus

This mineral is present in every cell of the body but is found mostly in bones and teeth with calcium. This mineral and calcium have an inverse relationship and increase in one causes a decrease in the other. Compounds of this mineral are used as a buffer system to maintain the pH of the blood, and is used to promote the effectiveness of many of the B vitamins. This is a component of DNA and RNA. Assist in normal nerve and muscle activity and is needed in carbohydrate metabolism the main excretion root for this mineral is the kidneys.

Normal serum blood levels are 2.4 - 4.1 mEq/L.

Hypophosphatemia

Condition associated with muscle weakness, especially with the respiratory muscles; bone and joint pain; and with disorientation and confusion.

When serum blood phosphorus levels drop below 2.4 mEq/dL.

Hyperphosphatemia

Condition that occurs most commonly as a result of renal insufficiency. Aluminum hydroxide may be used to decreased levels of this mineral.

Occurs when serum blood phosphorus level becomes more than 4.1 mEq/dL.

Magnesium

The fourth most abundant mineral in the body in the second most abundant caitian in the intracellular fluid. The majority of this mineral is found in the bone. Recognized as a cofactor in the activation of many enzymes. Promotes regulation of serum calcium, phosphate, and potassium levels. Essential for integrity of nerve tissue, skeletal muscle, and cardiac functioning.

Normal blood values are 1.5 to 2.5 mEq/L.

Hypomagnesemia

Conditon associated with decreased potassium levels because the kidneys tend to conserve this mineral by excreting more potassium.

Occurs when serum blood levels fall to less than 1.5 mEq/L

Hypermagnesemia

Condition that rarely occurs when kidney function is normal.

Occurs when magnesium blood levels exceed 2.5 mEq/L.

Bicarbonate

One of the main anions in the extracellular fluid. It is an alkaline electrolyte whose major function is the regulation of the acid-base balance acts as a buffer to neutralize acids in the body and maintain the 20:1 ratio of bicarbonate to carbonic acid that is needed to keep the body in homeostasis.

Normal level is 22 - 24 mEq/L.

Acid-base balance

The homeostasis of the hydrogen ion concentration in the body fluids.

Normal blood pH level

7.35 - 7.45

Respiratory acidosis

Any condition that impairs normal ventilation and prevents the respiratory system from eliminating the appropriate amount of carbon dioxide.

Respiratory alkalosis

Condition caused by the loss of excessive amounts of carbon dioxide, which result in a low carbonic acid level in the blood. The pH then increases because of the decrease in carbonic acid.

Metabolic acidosis

Conditon that occurs as a result of a gain of hydrogen ions or loss of bicarbonate. This causes the pH of the blood to fall.

Metabolic alkalosis

Condition that results when a significant amount of acid is lost from the body or the bicarbonate level increases.