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21 Cards in this Set

  • Front
  • Back

Immunization

Process of inducing immunity

What has the greatest impact on human health of all medical procedures?

Immunizations

In what two ways can immunity be acquired?

Naturally or artificially

Two types of immunity

Active


Passive

Active immunity

Follows antigen exposure


Natural active immunity results from what?

Infection

Artificial active immunity results from what?

Immunizations

Passive immunity

Antibodies from other

Natural passive immunity

During pregnancy, mother's IgG antibodies cross plecenta; breast milk contains Secretary IgA



No memory. Protection lost once antibodies degrade

Artificial passive immunity

Injection of antiserum, which contains antibodies.

Vaccine

Preparation of pathogen or its products

What is a vaccine used for?

1. To induce active immunity


2. Protect individual


3. Prevent spread in population

Herd immunity

Develops when critical portion of population is immune to disease; infectious agent unable to spread due to insufficient susceptible hosts.

Two general categories of vaccines

Attenuated


Inactivated

Attenuated vaccine

Elicits stronger immune response, but can sometimes cause disease



Replicates in recipient; disease undetectable or mild

Advantages of attenuated vaccines

Single dose usually induces long-lasting immunity due to microbe multiplying in body

Disadvantages of attenuated vaccines

Can sometimes cause disease in immunosuppressed individuals

Inactivated vaccine

Elicits weaker immune response, but cannot cause infections



Unable to replicate

Advantages of inactivated vaccines

Cannot cause infections or revert to pathogenic forms

Disadvantages of inactivated vaccines

No replication, so no amplification; immune response is limited

Polio virus

Three types


Infects throat and intestinal tract, invades blood


Can invade nerve cells and cause disease.