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32 Cards in this Set
- Front
- Back
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adrenergic agonists
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drugs that stimulate and mimic the actions of the sympathetic nervous system. sympathomimetics
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adrenergic receptors
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receptors sites for the sympathetic nurotransmitters noreepinephrine and epinephrine
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alpha-adrenergic receptors
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A1-adrenergic receptors located on postsynaptic effector cells
a2-adrenergic receptors located on presynaptic nerve terminals control the release of neruotransmitters |
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beta-adrenergic receptors
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are all located on postsynaptic effector cells
b1-located primarily in the heart b2-located in smooth muscle of the brochioles, arterioles, and visceral organs |
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catecholamines
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substances that can produce a sympathomimetic response. They are either endogenous catecholamines or synthetic catechomine drugs (dobutamine)
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dopaminergic receptor
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a thrid type of adrenergic receptor located in various tissues and organs and activated by the binding of the neurotransmitter dopamine, which can be either endogenous of a synthetic drug form
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mydriasis
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pupillary dilation, whether natural of drug induced
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ophthalmics
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drugs tht are used in the eye
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positive chronotropic effect
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an increase in heart rate
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positive dromotropic effect
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an increase in the conduction of cardiac electrial impulses through the atrioventricular node, which results in the trander of nerve action potentials from the atria to the ventricles.; this ultimately leads to a systolic hearbeat
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positive inotropic effect
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an increase in the force of contraction of the heart muscle
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sympathominmetics
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drugs used therapeutically that mimic the catecholamines epinephrine, norephinephrine, and dompamine
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synaptic cleft
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the space either between two adjacent nerve cell membrans or between a nerve cell membrane and an effector organ cell membrane
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dopamine is the only substance that can stimulate which receptors
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dilate vessels of the renal, mesenteric, coronary, and cerbral arteries
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b-adrenergic agonist response
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bronchial, gi and uterine smooth muscle relaxation
glycogenolysis cardiac stimulation |
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dopaminergic receptors
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stimulated by dopamine
causes dilation of the following blood vessels, resulting in increaed blood flow to: renal mesenteric coronary cerebral |
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blood vessels
constriction and dilation |
a1 constriction
b2 dilation |
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cardiac muscle
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b1 increased contractility
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AV node
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b1 increased heart rate
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SA node
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b1 increase heart rate
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muscle gi
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b2 decreased mobility
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sphincters gi
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a1 constriction
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bladder
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a1 constriction sphincter
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penis
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a1 ejaculation
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uterus contraction and relaxation
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b2 relaxation
a1 contraction |
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bronchial muscles
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b2 dilation
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liver
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b2 glycogenolysis
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pupils
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a1 dilation
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adrenergic drugs
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drugs that mimic the effects of the SNS neurotransmitters norepinephrine, epinephrine, and dopamine
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dobutamine
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it increase cardiac output by increasing contractility, which increase SV
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Catecholamines
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substances that can produce a sympathomimetic reaction
Dobutamine, Phenylephrine binds directly to teh receptor and causes a physiologic response |
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noncatecholamine adrenergic drugs (3)
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PHENYLEPHRINE, METAPROTERENOL, AND ALBUTEROL
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