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28 Cards in this Set

  • Front
  • Back
venous thrombus
clot within a vein
myocardial infarction
clot within a coronary artery
cerebrovascular accident/stroke
clot within an artery serving the brain
pulmonary embolus
clot within a pulmonary artery
valvular heart disease
disease of heart valves or replacement of a heart valve
angina
narrowing of the coronary vessels
indwelling devices
mechanical heart valves, stents
post-operative hemorrhage
bleeding following a surgical procedure
Von Willebrands Disease
most common hereditary platelet disorder, caused by a deficiency of a clotting protein
Hemophilia
hereditary lack of clotting factors VIII or IX
anticoagulant
prevention of clot formation (inhibits specific clotting factors)
anticoagulant/antiplatelet
prevention of clot formation by inhibition of platelet actions
thrombolytic
removal of an existing clot by dissolving with a drug
antifibrinolytic
promotion of clot formation by inhibiting the destruction of fibrin
A Prothrombin time (PT) is used to monitor which anticoagulant drug therapy?
warfarin sodium/coumadin
An Activated Partial Thromboplastin time (APTT) is used to monitor which anticoagulant drug therapy?
heparin sodium
Name 4 LMWHs
enoxaparin (Lovenox)
dalteparin sodium (Fragmin)
tinzaparin sodium (Innohep)
danaparoid sodium (Orgaran)
What is the action of pentoxifylline (Trental)?
reduces blood viscosity and increases the flexibility of RBCs
Aspirin inhibits ____________ a powerful inducer of platelet aggregation.
Thromboxane2
What is the action of dipyridamole (Persantine)?
Platelet inhibitor to prevent embolism in clients with prosthetic heart valves
What is the action of ticlopidine (Ticlid) and clopidrogrel Bisulfate (Plavix)?
ADP Receptor Blockers (prolongs bleeding time)
What is abciximab (ReoPro)used for?
prevent cardiac ischemia during coronary angioplasty
Name an enzyme necessary for platelet aggregation.
Glycoprotein IIb/Glycoprotein IIIa
Name 4 disorders that might prescribe thrombolytics as therapy?
acute myocardial infarction (MI)
pulmonary embolism
deep vein thrombosis (DVT)
acute ischemic cerebrovascular accident
What is a drawback of using Streptokinase?
Allergic reaction due to the fact that it is a foreign protein to the body.
Drugs used to prevent and treat excessive bleeding from a surgical site.
Antifibrinolytics
Name 2 drugs used for control of excessive bleeding post surgery.
aminocaproic acid (Amicar)
aprotinin (Trasylol)
A natural enzyme and a drug that dissolves blood clots.
tissue plasminogen activator (tPA)