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19 Cards in this Set

  • Front
  • Back
Genome
Complete set of genetic material in an organism
Why can DNA fit into the nucleus?
Because it wraps around histones and then a helical
What was the Human Genome Project?
A government funded project to determine the sequence of nucleotides in humans
Why do we want to know the sequence of nucleotides?
To determine the functions of resulting polypeptides
What is down syndrome?
An accident in meiosis(usually 1) in which 3 chromosomes are found
What is nondisjunction?
When homologous chromosomes or sister chromatids fail to seperate during meiosis
What effects the chances of having a baby with down syndrome?
A woman's age
What do genetic disorders involve?
Changes in the makeup of one or more pairs of gene alleles
What is a frame shift?
The same as insertion/deletion
Why is trisomy 21 the most common?
Because the baby is able to survive; however, it has down syndrome
What are the four types of damaged chromosomes?
Duplication, deletion, inversion, and translocation
What is duplication?
When part of a chromosome is repeated
What is deletion?
Occurs when part of a chromosome is lost
What is inversion?
Reversal of segments of a chromosome
What is translocation?
When a fragment of one chromosome attaches to a homologous chromosome
What is another name for jumping genes?
Transposons
What is the difference between growth factors and tumor-suppressor genes?
Growth factors initiate cell division; tumor suppressor genes stop it
What is an oncogene?
A cancer causing cell
What do carcinogens do?
Cause cancer