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27 Cards in this Set

  • Front
  • Back
During Luteal phase of the Menstral cycle, what is the main bacteria present?
Lactobacillus
What is the most common infection of the female genital tract, and what organism?
Bacterial vaginosis caused by Gardenerella vaginosis.
What are the three main bacteria that cause STD's?
Neisseria Gonorrhea, Chlamydia trachomatis, and treponema pallidum.
What are the bacteria that can cause PID (Pelvic inflammatory disease).
N. Gonorrhea and Chlamydia - both cause acute and chronic PID.

Coliforms, and anarobes cause - Chronic PID
What bacterium can cause Congenital and Perinatel infections.
Treponema Pallidum - cuases osteochhondritis, hepatosplenomeagaly, mental retardation.

Group B streptococus and
Lysteria monocytogenes cause Neonatal sepsis and meningitis
Which two organisms can cause PID.
genococcus and chlamydia
How can PID cause ectopic pregnancy or even infertility?
inflammation and fibrosis causes damage in fallopian tube(s) and ova can not reach uterus to implant or implants in the fallopian tube (ectopic pregnancy).
How can PID be diagnosed?
Cervical discharge and cervical tenderness, palpable pelvic mass, fever, raised WBC, CRP, and ESR.
-endocervical swab for genococcus and chlamydia and blood culture.
What antibiotics are used to treat PID?
doxycycline and Metronidazole, but if no response clindamycin and ciprofloxacin
Bacterial vaginosis?
Polymicrobial condition w/ Mycoplasma hominis and anaerobes that overwhelm lactobacillus populatio and vagina and produce a gray fishy odor.
What percentage of chlamydia infections seek medical advice?
10% which is bad because these can be asympomatic in females facilitating ignorantly the passing of the STD.
During follicular phase of the menstrual cycle what organism(s) are present?
Bacteroides, coliforms, group B strep and lactobacillus.
What organisms can cause congenital and perinatal infections?
Treponema Pallidum, Group B Strep, Listeria Monocytogenes.
Neisseria Gonorrhea
Infects mucosal columnar and cubodial epithelial cells of genital tract, rectum, throat, and eyes.
N. Gonorrhea invades epithelium cells in what manner?
Attaches via adhesins in cell wall and outer membrane Opa proteins. which allows invasion of epithelium and strong neutrophil invasion, micro-abcesses, and pus. Can cause PID. (human specific pathogen).
Antibiotics used for N. Gonorrhea.
Amoxycillin, doxycycline, azithromycin
Antibiotics used for Chlamydia trachomatis.
doxycycline and azithromycin
antibiotics for treponema pallidum
benzypenicillin
Why is Chlamydia considered the hidden epidemic.
most common of STDs, three times the number of reported cases of gonorrhea. Carriage rate in females and males is high (asymptomatic).
chlamydia diagnosis
swap in chlamydia transport medium, serological Elisa test, and confirmation w/ PCR.
primary syphilis
painless ulcer and invades blood to be widely distributed.
2ndary syphilis
manifests rash weeks after initial phase, lesions harboring many bacteria on skin.
Latent phase syphilis
no symptoms, but during first four years relapses to the infection can occur
tertiary syphilis
considered latent phase, but can manifest as neurosyphilis or cardiac syphilis
Congenital infection:syphilis
about 50% of babies born with CS are asymptomatic. prenatal screen by Elisa for treponema antibodies should be done.
Borrelia burgdorferi causes
lyme disease, classic migrating bulls eye rash, and can cause arthritis later on.
Septic arthritis
bacteria invade cartilage and destroy it. S. aureus produces chondrocyte protease that can destroy cartilage.