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37 Cards in this Set

  • Front
  • Back

Is a 50% W/O emulsion

Eucerin

The skin is its target organ

Topical dermatological product

Has the capacity to absorb up to 3 times its weight in water and help incorporate a water soluble drug

Absorption bases

Is lanolin processed to reduce the contents of free lanolin alcohols

Modified Lanolin

n in PEG formula represents what?

Number of oxyethylene groups

Selection of the appropriate base

Release rate of drug from ointment base


Tooical or percutaneous absorption


Desirability of occlusion of moisture from skin


Stability of drug


Effect


Desire for a bse easily removed


Characteristics of the surface


Compedial requirements for ointments

Microbial Content


Minimum fill


Packaging, storage and labelling


Viscosity


In vitro drug release

Opthalmic ointments must undergo these tests

Sterility


Metal particles

This product must meet the requirements of the tests for absence of staphylococcus aureus and psuedomonas aeruginosa

Betamethasone valerate ointment

Determination of the net weight or volume of the contents of filled containers

Minimum fill

Proper packaging for semi solid dosage forms

Large-mouth ointment jars/metal or plastic tubes


Well-closed container


Cool place


Opaque or light resistant

Semisolid preparations containing one or more medicinal agents

Creams

Semisolid systems consisting of dispersions of small or large molecules in an aqueous liquid vehicle

Gels (a. k. a jellies)

Examples of gelling agents

Carbomer 934, tragacanth

Are high molecular weight water-soluble polymers of acrylic acid

Carbomers

This carbomer yields the highest Viscosity

Carbomer 940

Magma

Two phase gels having flocculation

Adm by teat infusion to tx mastitis

Antibiotic-containing gels

Clear, colorless gel containing testosterone

Androgel 1.62%

This gel aids in the rapid penetration of many active drugs through the skin

Pluronic lecithin organogel

Semisolid adhesive masses spread on a backing paper, fabric, moleskin, or plastic.

Plasters

Adhesive material of plasters

Rubber base or synthetic resin

Unmedicated plasters provide what? Mediacted plasters provide what?

Unmedicated--protection


Medicated--effects

Used on the toes for the removal of corns

Salicyclic acid plasters

Percent of gelatin, glycerin, water and an added substance in glycerogelatins.

Gelatin--15%


Glycerin--40%


Water--35%


Added substance--10%

Applied to the skin for long term

Glycerogelatins

Tx of varicose ulcers

Zinc gelatin

Are made of clear or opaque glass or ir plastic

Ointment jars

Colors of opaque jars

Dark green


Porcelain white


Amber

Different features or advantages between LDPE and HDPE

LDPE--soft and resilient, good moisture barrier


HDPE--superior moisture barrier, less resilient

Cylindrical bodies of plastic tubes are made by

Extrusion

Process where the semisolid is filled into the chamber and the product is delivered into the tube.

Caulking gun

How long does ophthalmic ointment retain in the compared to ophthalmic solutions

Ointment - - 5%/minute


Solution - - 16% per minute

Most often mixtures used as base in medicated and unmedicated ophthalmic ointments.

White petrolatum and liquid petrolatum

Bases used in anorectal ointments

Combination of peg 300 and 3350

Intranasal adm used in the tx of vit b12 deficiency and pernicious anemia

Cyanocobalamin

How many times is cyanocobalamin administered?

0.1 ml of the gel contains 500mg cyanocobalamin taken once weekly