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10 Cards in this Set

  • Front
  • Back
What is asthma?
a chronic inflammatory disorder of the airways
How is asthma characteriazed?
periodic attacks of wheezing, SOB, chest tightness, and coughing
What is atopy?
genetic predisposition to allergy including asthma
What cells play a role in asthmatic reactions?
eosinophils, mast cells, T lymphocytes, epithelial cells
What are bronchospastic triggers for asthma?
cold air, exercise, cigarette smoke, air pollutants, and emotions
What are inflammatory triggers for asthma
airways primed to be hyperresponsive to allergic/ nonallergic stimuli including pet dander, dust mites, and cockroach antigen
What occurs during an early/acute phase response?
immediate bronchoconstrictio, symptoms w/i 10-20 minutes
What cells and mediators are early/acute phase responses to asthma caused by?
chemical mediators, histamine, IgE-coated mast cells
Describe the late phase response of asthma?
occurs 4-8 hours after trigger, can last days to week, inflammation/airway hyperresponsiveness prollong/exacerbate the attack
What cells are involved in late phase response?
mast cells, macrophage, epithelial cells, eosinophils (damage to epithelial cells can occur)