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19 Cards in this Set
- Front
- Back
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The native microbial forms that an individual harbors.
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Normal flora |
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A condition in which pathogenic microbes penetrate host defenses, enter tissue and multiply.
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an Infection |
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An infection that causes damage or disruption to tissues and organs
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an Infectious Disease |
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What areas of the body have normal flora?
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Most areas of the body in contact with the outside environment harbor Normal flora. (Skin, vagina, ear and canal, eye lids and lash follicles etc.) |
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What areas of the body are normally free of bacteria?
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Internal organs, tissues and fluids |
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· What is the difference between a transient and resident microbiota?
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Transient is only present for a period of time and resident becomes established. |
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Bacterial flora benefit host by preventing over growth of harmful microbes |
Microbial antagonism |
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this occurs when flora is introduced to a site that was previously sterile |
Endogenous infection |
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How are normal flora maintained? |
Probiotics |
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What are the major factors involved in the development of an infection? |
1. finding a portal 2. Attaching firmly 3. Surviving host defenses 4. Causes of damage and disease 5. Exiting Host |
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True pathogen |
capable of causing disease in healthy persons with normal immune systems |
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Opportunistic Pathogen |
cause disease when the host's defenses are compromised or when they go in the part of the body that is not natural to them. |
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what are some usual portals of entry for pathogens |
Skin, GI tract, Respiratory tract, urogenital tract, endogenous biota, and trans-placental. |
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What is the difference between endogenous and exogenous agents? |
exogenous agents originate from source outside the body, while endogenous agents already exist on or in the body (Normal Flora) |
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The estimated number of microbial cells or units required to establish an infection. |
Infectious dose |
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What are some methods that microbes use to attach to a host? |
Fimbrae, Flagella, Glycoccalyx, cilia, suckers, hooks, barbs. |
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Traits used to invade and establish themselves in the host, also determine the degree of tissue damage that occurs - Severity of disease. |
Virulence Factors |
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Dissolve extracellular barriers and penetrate threw or between cells. |
Exoenzymes |
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What is the difference between the endotoxin and the exotoxin? |
Endotoxin is not secreted and released after the cell is damaged. Exotoxin is secreted by living bacterial cell into the infected tissue. |
