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49 Cards in this Set

  • Front
  • Back

functions of upper respiratory system?

collects air, filters, delivers oxygen and carbon dioxide

functions of lower respiratory?

gas exchange

protective components of nasal cavity?

hairs and ciliated mucous membrane to filter and trap microbes

protective components of pharynx?

lined with ciliated mucous membrane that pushes contaminants to digestive system

protective components of tonsils?

aggregations of lymphoid

is the upper respiratory system typically sterile and the lower system highly colonized?

no, other way around

protective components of the lower respiratory?

ciliated cells of mucous, alveolar macrophages, secretory antibodies

normal microbiota of the respiratory system include..

haemophilus influenzae-colonizes the nose



staphylococcus aureus



streptococci-nose and throat



corynebacterium diptheriae

the viridian's group are what and what type of hemolytic?

alpha heomlytic,


S. mutans, S. salivarius

beta hemolytic streptococci?

S. pyogenes


S. agalactiae-meningitis


S. equi


S.faecalis


S.anginosus


S.canis

group a streptococci virulence factors-s.pyogenes?

m proteins-- spiky surface projections to resis phagocytosis. inactivate C3b--basis of rheumatic fever



hyaluronic acid-- capsule for camouflage



streptokinases--declotting agents



C5a peptidase--inactivates peptide C5a



Pyrogenic toxins--fever



Streptolysin-- causes beta hemolysis

how are streptococcal diseases spread?

respiratory droplets

most effective treatment and why?

penicillin, streptococci are less resistant to penicillin that staphylococci

corynebacterium diptheriae produces what toxins and prevents what to result what?

diphtheria toxin which prevents protein synthesis and results sore throat

oozing fluid can harden into what and can further damage what

hardens into pseudomembrane and obstruct airway

was diphtheria the leading cause of death in children or adults in the 1900's US?

children

what is sinusitis?

pain and pressure in sinus--adults

what is otitis media?

pain in ears--in children through immunity development

most common cause of the cold

rhinoviruses

what are bacterial pneumonias?

inflammatory illness in lungs with fluid filled alveoli and bronchioles

pneumococcal pneumonia causes?

chest pain, short breathing

what type of hemolysis in pneumococcal pneumonia?

alpha-hemolytic

primary artypical mycoplasma pneumonia causes what?

fever, malaise, sore throat, sweating

virulence factors and spread how>

adhension protein


nasal secretions

treated with? (2)

tetracycline and erythromycin

klebsiella pneumonia is what type of pathogen and what virulence factor?

opportunistic



thick capsule

what type of individuals are at great risk for klebsiella pneumonia?

immunocopromised individuals

Legionnaires pneumonia symptoms and what do they do?

complications to vommiting, CNS, liver, and kidneys, causes tissue damage and inflammation

where does L.pneumophila thrive?

ubiquitous, aquatic, gram- bacterium that thrives in warm water

What is the minimum infective dose for tuberculosis?

10 cells

what are the 3 types of tb?

primary-initial case=50% fatality, weight loss, cough



secondary- re-established tb



disseminated- tb in multiple systems

tb is the leading killer of individuals with what disease?

HIV+

Characteristics of pertussis

it is the whooping cough, caused by bordetella pertussis

virulence factors of pertussis?

pertussis toxin


adenylate cyclase toxin


dermonecrotic toxin


trachel cytotoxin

4 phases of whooping cough?

incubation


catarrhal (inflammation)


paroxysmal (coughing)


convalescent

The influenza A genome contains how many genes, proteins, and RNA pieces?

11 genes, 11 proteins, 8 pieces of RNA


Main complaint about influenza?

aching

What was the swine flu?

a 2009 pandemic of influenza H1N1

mutations of influenza can occur via 2 main processes

antigenic drift


antigenic shift

What is the most common early childhood respiratory disease?

Respiratory syncytial Virus Infection

Diagnosis of RSV is made by?

immunoassay combined with signs of respiratory distress

what is the primary resevoire of the hantavirus?

peromyscus maniculatus

HPS is transmitted to humans through what process? but it cannot be transmitted from what to what?

aerosolization



person to person or from animals

found in what regions of the us?

utah, AZ, CO, NM

What disease resembles pneumonia or tb?

coccidiodomycosis

how does the pathogen assume in the body>

in yeast form at human body temp, inhaled through from spores of soil

Pneumocystis pneumonia is what type of infection?

yeast like fungus

PCP is most common to what type of people?

HIV+

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