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36 Cards in this Set

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what are formed elements?
* Formed elements – living blood "cells" suspended in plasma(non-living fluid matrix)
•  Erythrocytes (red blood cells, or RBCs)
•  Leukocytes (white blood cells, or WBCs)
•  Platelets
what are % of formed elements from least to most dense?
Plasma
• 55% of whole blood
Formed elements
• Least dense component
Buffy coat
• Leukocytes and platelets
• <1% of whole blood Erythrocytes
• 45% of whole blood (hematocrit)
• Most dense component
what are the functions of blood?
Functions include
– Distributing
substances
– Regulating blood
levels of
substances
– Protection
what are the distributing functions?
Delivering O2 and nutrients to body cells
•  Transporting metabolic wastes to lungs
and kidneys for elimination
•  Transporting hormones from endocrine
organs to target organs
what is the regulating function?
Maintaining body temperature by
absorbing and distributing heat
•  Maintaining normal pH using buffers;
alkaline reserve of bicarbonate ions
•  Maintaining adequate fluid volume in
circulatory system
what is the protection function?
*MAKES SCARES

Preventing blood
loss
– Plasma proteins
and platelets
initiate clot
formation
•  Preventing infection
– Antibodies
– Complement
proteins
– WBCs
what is the % water in plasma?
90%
what are RBCs and its characteristics?
**most abundant
-no nuclie (anucleate)
-filled with hemoglobin (Hb) *binds reversibly with oxygen
-contains protein spectrin for flexibility
-contributes to blood viscosity
-dedicated to respiratory gas transport.
what formes red bone marrow?
Hematopiesis
What name is given to the formation of red blood cells?
erythropoiesis
What is this? Name some important characteristics-
-Its a red blood cell (RBC) erythrocyte
- has no nuclei or other organelles "anucleated"
-biconcave
-filled with hemoglobin (hb) for gas transport.
-has spectrin for flexibility
-lifespan 100-120 days
to few (RBC's): to many:
hypoxia;viscosity
What is released by kidneys some from liver in response to hypoxia?
The hormone Erythropoietin (EPO)
-rapid maturation of committed marrow cells

Anemia

has abnormally low O2 carrying capacity.

what are causes of anemia?
-blood loss
-low RBC's production
-high RBC distribution
what disease is caused by single amino acid change in the bata chain? and what amino acid?
disease: sickle-cell anemia.
amino acid: hemoglobin.

A blood disorder involving less than normal amounts of an oxygen-carrying protein.

thalassemias

what is another name for WBC's"white blood cells"?
leukocytes
what are leukocytes functions & characteristics ?
•  Make up <1% of total blood volume
•  Function in defense against disease
– Can leave capillaries via diapedesis



  Leukocytosis:
WBC count over 11,000/
mm3
– Normal response to infection
what leukocytes are granucytes?
neutrophils,eosinophils, basophils.
what leukocytes are agranulocytes?
lymphocytes, monocytes
basophil
eosinophil
small lymphocyte
neutrophil
monocyte

name the blood type?

a.(AB)


b.(B)


c.(A)


d.(O)

most numerous leukocyte
neutrophil
increases in numbers during prolonged infections
monocyte
primarily water,noncellular; the matrix of blood
plasma
many formed in lymphoid tissue
lymphocyte
releases histamine promotes inflammation
basophil
number rises during infections
eosinophil
precursor cell of platelets
megakaryote
average blood volume of a
male
female
5.6 ; 4.5