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22 Cards in this Set
- Front
- Back
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Neutrophilic Leukocytosis
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Neutrophil Count > 7000uL
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Neutrophilic Leukocytosis
When: |
1. Infection ( acute Appendicitis)
2. Sterile inflammation with necrosis (acute MI) 3. Drugs Corticosteroids |
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Neutrophilic Leukocytosis
Patho |
1. Increased Bone Marrow production or release of neutrophils
2. Decreased activation of neutrophil adhesion a-less neutrophils adhere to endo cells b-Ex- Corteco, Cathecolamines, Lithium |
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Neutropenia
Define |
Neutrophil count < 1500
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Neutropenia
When |
1. Aplastic Anemia
2.Immune destruction ----EX: SLE 3. Septic Shock |
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Neutropenia
Patho |
1. Decreasd production
2. Increased production ( macrophage or cpmplememt 3. Activation of neutrophil adhesion molecules ---Endotoxins Increase the neutrophils adherence to endo cells |
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Eosinophila
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Count > 7000/ul
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Eosinophila
When |
1. Type 1 Hyper
2. Invasive Helmiths ( hookworkm) 3. Hypocorticolism ( addison or Polyarteritis Nodosa) |
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When would you think Eosinophila but not
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Pinworms and Adult Ascariasis do not b/c not invasive
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Eosinophila
Patho |
1. Release of eosinophil chemotatic factor from mast cells ( type 1)
2. No sequestering of esinophils in lymph ( hypocortisolism |
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Eosinopenia
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1.Hypercorticolism ( Cushings or Corticosteroids
2. Corticosteroids sequester eosinophils in lymph nodes |
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Basophilia
Define |
Count >110/uL
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Basophilia
When |
Chronic myeloiproliferative disorders
Polycythemia vera |
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Corticosteroids do what to WBC count
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Neutrophilic leukocytosis
Eosinopenia Lympopenia |
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Age ranges for Leukemias
New born to 14 |
ALL
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Age ranges for Leukemias
15-39 |
AML
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Age ranges for Leukemias
40-60 |
1. AML >60%
2. CML ~ 40% |
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Age ranges for Leukemias
>60 |
CLL
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Monocytosis
Define |
Count > 800/uL
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Monocytosis
Causes |
1. Chronic Infection ( TB)
2.Autoimmune Disease ( RA) 3. Malignancy ( Carcinome, Malignant Lymphoma) |
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Monocytosis
Patho |
Response to Chronic inflammation or malignancy
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Leukemias ( Acute or Chronic)
Define |
Malignant disease of bone marrow stem cells that may involve all celline lines
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