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117 Cards in this Set

  • Front
  • Back
sarcolemma
plasma membrane of a muscle fiber
sarcoplasm
cytoplasm of a muscle fiber
myofibrils
a bundle of protein myofilaments (microfilaments)
glycogen
a starchlike carbohydrate that provides energy for the cell during heightened level of exercise.
in the sarcoplasm.
an energy storing polysaccharide abundant in muscle
myoglobin
red pigment of muscle that sores oxygen until needed for muscular activity
in the sarcoplasm
muscle fibers have ----------------nuclei pressed against the-----------
multiple flattened or sausage shaped nuclei presses againt the inside of the sarcolema
myoblast
stem cells
during embryonic development myoblasts-----------
fuse to produce each muscle fiber, each contributing a nucleus
satelite cells
myoblasts that remain unspecialized
located between the muscle fiber and the endomysium
smooth ER
sarcoplasmic reticulum
sarcoplasmic reticulum
forms a network around each myofibril
the smooth ER of a muscle fiber ; calcium ion reservoir
terminal cisternae
dilated end sacs of sarcoplasmic reticulum which cross the muscle fiber from one end to the other.
adjacent to a T tubule
transverse (T) tubules
a tunnel-like extension of the sarcolemma extending from one side of the muscle fiber to the other; conveys electrical signals from one side of the cell surface to the other
triad
a T tubule and its associated 2 terminal cisternae
the SR is a reservoir for
calcium ions
the SR has gated channels that open at the right time to release
a flood of Calcium ions into the cutoplasm, where the calcium activates the muscle contraction process
the T tubule signals the SR when to release
calcium bursts
myofibril
long protein cords that fill most of the muscle cell
myofilaments
each myofibril is a bundle of protein microfilaments called
3 types of myofilaments
thick- myosin
thin - actin
elastic
each myofibril is divided into segments called
sarcomeres
------- are contractile proteins because they
myosin and actin
accomplish the shortening of the muscle fiber
---------are called regulatory proteins because they
tropomyosin and troponin
act like a switch to determine when the can contract or not contract
shaped like a golf club
myosin moloecule
like a bead necklace
f actin
has an active site that can bind to the head of a myosin head
g actin
a regulatory protein. blocks active sites of some g actins when muscle fiber is relaxed & prevents myosin from binding to them
tropomyosin
a regulatory protein. acts as a calcium receptor
a calciun binding protein that is bound to every tropomysin molecule
troponin
each myofibril is divided into segments called
sarcomeres
allows more calcium ion storage
terminal cisternae
formed by the invagination of sarcolemma (plasma membrane)
transverse tubule
microfilaments of muscle cells
myofilament
genetic defects in dystrophin are responsible for the disabling disease
muscular distrophy
myofilament
a threadlike coplex of several hundred contractile protein molecules
thick filament
a miofilament about 11nm in diameter composed of bundled myosin molecules
thin filament
a miofilament about 5 to 6 nm in diameter composed of actin, troponin and tropomyosin
f actin
a fibrous protein made of a long chain of g actin molecules twisted into a helix; main protein of the thin miofilament
striations
alternating light and dark transverse bands across a myofibril
A band
dark band formed by parallel thick filaments that partly overlap the thin filaments
H band
a lighter region in the middle of an a band that contains thick filaments only; thin filaments do not reach this fare into an a band in relaxed muscle
m line
a dark line in the middle of an h band; origin of thick filaments
i band
a light band composed of thin filaments only
z disc
a protein disc to which thin filaments and elastic filaments are anchored at each end of a sarcomere; appears as a narrow dark line in the middle of the i band
sarcomere
the distance from one z disc to the next; the contractile unit of a muscle fiber
if the nerve supply to a skeletal muscle is severed, the muscle becomes paralyzed and will undergo
denervation atrophy (shrinkage)
skeletal muscles are innervated by nerve cells called
somatic motor neurons
the place where the axon meets the muscle cell is called the
neuromuscular junction
somatic motor neurons axons are called
somatic motor fibers
lead to skeletal muscles
somatic motor fibers
1 nerve fiber (or motor neuron) and all the muscle fiber innervated by it are called a
motor unit
the point where a nerve fiber meets it junction
synapse
a functional connection between the distal end of a nerve fiber and the middle of muscle fiber
-when the target cell is a muscle fiber the synapse is called a
neuromuscular junction or motor end plate
the dilated tip of a nerve fiber; contains synaptic vesicles
-at each synapse the nerve fiber end in a bulbous swelling called a
synaptic knob
the synaptic knob doesn't directly touch the muscle fiber but is seperated by a narrow space called a
a gap between the synaptic knob and the sarcolemma
synaptic cleft
spherical organelles in the synaptic knob filled with ACh
synaptic vesicle
the nerotransmitter released by a somatic motor fiber that stimulates a skeletal muscle fiber
acetylcholine ACh
ACh receptor
a transmembrane protein in the sarcolemma of the neuromuscular juntion that binds to ACh
acetylcholinesterase AChE
an enzyme in the sarcolemma and basal lamina of the muscle fiber in the synaptic region; responsible for degrading ACh and stopping the stimulation of the muscle fiber
if the nerve supply to a muscle is severed, the musclew becomes paralyzed and will undergo
denervation atrophy (shrinkage)
a deficiency in ACh receptors leads to muscle paralysis in the disease
myasthenia gravisb
a process in which action potentials in the nerve lead to action potentials in the muscle fiber; it can be divided into 5 steps
excitation
refers to the events that link the action potentials on the sarcolemma to activation of the myofilaments; this process has 4 steps that follow----
excitation-contraction coupling
excitation
the step where muscle fiber develops tension and may shorten
this process can be divided into four steps that follow-----
contraction
excitation-contraction coupling
myosin releases the ADP and phosphate and flexes into a bent, low energy position, tugging the thin filament along with it; this is called the
power stroke
hydrolyzing ATP and recocking
recovery stroke
where is pyruvic acid converted to lactic acid
cytosol
the break down of a glucose molecule to 2 molecules of pyruvic acis is called--------
and has a net yield of-------
glycolysis
2 ATP
aerobic respiration is limited by
and produces a total of
oxygen availibility
38 ATP per glucose molecule
what is the waste product of
1.anaerobic respiration----
2. aerobic respiration-------
1. lactic acid
2. CO2
in aerobic respiration pyruvic acid enters the----------- where it is further broken down into-------
mitochondria
CO2 and H2O
in glycolysis what does glucose break down to
pyruvic acid
what is the only advantage of anaerobic respiration
not limited by O2 availability
3 ways muscle cells are provided with ATP
1. phosphagen system
2. anaerobic respiration (glycogen-lactic acid system, fermentation)
3. aerobic respiration
a single muscle fiber may contain--------------thick filaments.
when the fiber is contracting each filament breaks down to roughly --------------
15 billion thick filaments
2500 ATP molecules per second
which 2 systems are responsible for getting O2 out to the muscle cells
respiratory and circulatory systems
muscle cells store
ATP and CP
myoglbin
glycogen
oxygen binding pigment that give muscles tissue its reddish color
myoglobin
the ATP and CP stored in muscle cells are referred to as the
phosphagen system
polysaccharide (macromolecule composed of many glucose molecules bonded together)
glycogen
which system provides immediate energy
phosphagen system
which system provides most of the energy in sports involving intense bursts of energy lasting between 15 seconds and 1 min
anaerobic repiration
which system provides immediate energy for sports 15 seconds or less
football weight lifting, sprinting swim races running to 1st base ect..
phosphagen system
which system provides long term energy sports where endurance rather than power is a goal jogging
aerobic respiration
anaerobic respiration is sometimes called
glycogen-lactic acid system
H2CO3
carbonic acid
HCO3-
bicarbonate ions
H+
hydrogen ions
creatine phosphate + ADP =
ATP + creatine
where is lactic acid converted back to pyruvic acid
liver
synergist
a muscle that aids the prime mover, may stabilize a joint or modify direction of the movement
antagonist
muscle that opposes the prime mover, often maintains some tension during movement limiting the speed or range of the movement to protect injury
fixator
muscle that prevents bone from moving; allowing other muscles attached to it to pull on something else
origin
the bony site of attachment at the relatively stationary end
insertion
attachment site at the more mobile end
belly
thicker middle region of a muscle
intrinsic muscle
is entirely contained within a particular region having both origin and insertion there
extrinsic muscle
acts upon a certain region but has its origin elsewhere. the forearm muscles that control the fingers
---------- the muscle ends short of the bone, and the gap is bridged by a fibrous band or sheet called a ---------
indirect attachment
tendon
in some cases the tendon is a broad sheet called an
ex tendon beneath scalp
aponeurosis
in some places groups of tendons from separate muscles pass under a band of CT called a
ex the one that encircles the wrist like a bracelet
retinaculum
--------------the muscular tissue seems to emerge directly from the bone as seen by the naked eye, but the muscle stops short of the bone and the gap is filled by -------------
direct (fleshy) attachment
collagen fibers
skeletal muscle contractions 4 overlapping functions
1 movement
2 stability
3 control of bodies openings and passages
4 heat production- prod 85% of body heat
four connective tissue components from superficial to deep
fascia
epimysium
perimysium
endomysium
CT that surrounds each muscle fiber
endomysium
-------thicker CT that wraps muscle fibers into bundles called---------
perimysium
fascicles
fibrous sheath that surrounds the entire muscle
epimysium
is a sheet of CT that separates neighboring muscles or muscle groups from each other and from subcutaneous tissue
fascia
fascicles determine
the strength of a muscle and the direction of its pull
fusiform
thick in middle and tapered at each end
ex biceps brachii
parellel
fairly uniform width and parallel fascicles
ex rectus abdominis, sartorius
triangular (convergent)
muscles are fan shaped, broad at origin and narrow at insertion
ex pectoralis major
pennate
muscles are feather shaped, with fascicles inserting obliquely on a tendon that runs the length of the muscle
unipennate
muscles have fascicles approaching the tendon from 1 side
ex extensor digitorium longus
bipennate
muscles have fascicles approaching the tendon from both sides
ex rectus femoris
multipennate
muscles are shaped like a bunch of feathers with quills converging on a single point
ex deltoid
circular (sphincters)
form rings around certain openings
ex obicularis oculi
the --------- of a muscle refers to the identity of the nerve that stimulates it
name the 2 general groups of nerves
innervation
spinal nerves
cranial nerves