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117 Cards in this Set
- Front
- Back
sarcolemma
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plasma membrane of a muscle fiber
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sarcoplasm
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cytoplasm of a muscle fiber
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myofibrils
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a bundle of protein myofilaments (microfilaments)
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glycogen
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a starchlike carbohydrate that provides energy for the cell during heightened level of exercise.
in the sarcoplasm. an energy storing polysaccharide abundant in muscle |
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myoglobin
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red pigment of muscle that sores oxygen until needed for muscular activity
in the sarcoplasm |
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muscle fibers have ----------------nuclei pressed against the-----------
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multiple flattened or sausage shaped nuclei presses againt the inside of the sarcolema
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myoblast
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stem cells
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during embryonic development myoblasts-----------
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fuse to produce each muscle fiber, each contributing a nucleus
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satelite cells
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myoblasts that remain unspecialized
located between the muscle fiber and the endomysium |
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smooth ER
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sarcoplasmic reticulum
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sarcoplasmic reticulum
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forms a network around each myofibril
the smooth ER of a muscle fiber ; calcium ion reservoir |
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terminal cisternae
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dilated end sacs of sarcoplasmic reticulum which cross the muscle fiber from one end to the other.
adjacent to a T tubule |
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transverse (T) tubules
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a tunnel-like extension of the sarcolemma extending from one side of the muscle fiber to the other; conveys electrical signals from one side of the cell surface to the other
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triad
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a T tubule and its associated 2 terminal cisternae
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the SR is a reservoir for
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calcium ions
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the SR has gated channels that open at the right time to release
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a flood of Calcium ions into the cutoplasm, where the calcium activates the muscle contraction process
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the T tubule signals the SR when to release
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calcium bursts
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myofibril
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long protein cords that fill most of the muscle cell
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myofilaments
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each myofibril is a bundle of protein microfilaments called
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3 types of myofilaments
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thick- myosin
thin - actin elastic |
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each myofibril is divided into segments called
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sarcomeres
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------- are contractile proteins because they
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myosin and actin
accomplish the shortening of the muscle fiber |
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---------are called regulatory proteins because they
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tropomyosin and troponin
act like a switch to determine when the can contract or not contract |
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shaped like a golf club
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myosin moloecule
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like a bead necklace
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f actin
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has an active site that can bind to the head of a myosin head
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g actin
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a regulatory protein. blocks active sites of some g actins when muscle fiber is relaxed & prevents myosin from binding to them
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tropomyosin
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a regulatory protein. acts as a calcium receptor
a calciun binding protein that is bound to every tropomysin molecule |
troponin
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each myofibril is divided into segments called
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sarcomeres
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allows more calcium ion storage
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terminal cisternae
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formed by the invagination of sarcolemma (plasma membrane)
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transverse tubule
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microfilaments of muscle cells
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myofilament
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genetic defects in dystrophin are responsible for the disabling disease
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muscular distrophy
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myofilament
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a threadlike coplex of several hundred contractile protein molecules
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thick filament
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a miofilament about 11nm in diameter composed of bundled myosin molecules
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thin filament
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a miofilament about 5 to 6 nm in diameter composed of actin, troponin and tropomyosin
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f actin
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a fibrous protein made of a long chain of g actin molecules twisted into a helix; main protein of the thin miofilament
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striations
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alternating light and dark transverse bands across a myofibril
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A band
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dark band formed by parallel thick filaments that partly overlap the thin filaments
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H band
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a lighter region in the middle of an a band that contains thick filaments only; thin filaments do not reach this fare into an a band in relaxed muscle
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m line
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a dark line in the middle of an h band; origin of thick filaments
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i band
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a light band composed of thin filaments only
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z disc
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a protein disc to which thin filaments and elastic filaments are anchored at each end of a sarcomere; appears as a narrow dark line in the middle of the i band
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sarcomere
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the distance from one z disc to the next; the contractile unit of a muscle fiber
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if the nerve supply to a skeletal muscle is severed, the muscle becomes paralyzed and will undergo
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denervation atrophy (shrinkage)
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skeletal muscles are innervated by nerve cells called
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somatic motor neurons
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the place where the axon meets the muscle cell is called the
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neuromuscular junction
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somatic motor neurons axons are called
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somatic motor fibers
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lead to skeletal muscles
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somatic motor fibers
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1 nerve fiber (or motor neuron) and all the muscle fiber innervated by it are called a
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motor unit
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the point where a nerve fiber meets it junction
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synapse
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a functional connection between the distal end of a nerve fiber and the middle of muscle fiber
-when the target cell is a muscle fiber the synapse is called a |
neuromuscular junction or motor end plate
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the dilated tip of a nerve fiber; contains synaptic vesicles
-at each synapse the nerve fiber end in a bulbous swelling called a |
synaptic knob
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the synaptic knob doesn't directly touch the muscle fiber but is seperated by a narrow space called a
a gap between the synaptic knob and the sarcolemma |
synaptic cleft
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spherical organelles in the synaptic knob filled with ACh
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synaptic vesicle
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the nerotransmitter released by a somatic motor fiber that stimulates a skeletal muscle fiber
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acetylcholine ACh
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ACh receptor
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a transmembrane protein in the sarcolemma of the neuromuscular juntion that binds to ACh
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acetylcholinesterase AChE
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an enzyme in the sarcolemma and basal lamina of the muscle fiber in the synaptic region; responsible for degrading ACh and stopping the stimulation of the muscle fiber
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if the nerve supply to a muscle is severed, the musclew becomes paralyzed and will undergo
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denervation atrophy (shrinkage)
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a deficiency in ACh receptors leads to muscle paralysis in the disease
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myasthenia gravisb
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a process in which action potentials in the nerve lead to action potentials in the muscle fiber; it can be divided into 5 steps
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excitation
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refers to the events that link the action potentials on the sarcolemma to activation of the myofilaments; this process has 4 steps that follow----
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excitation-contraction coupling
excitation |
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the step where muscle fiber develops tension and may shorten
this process can be divided into four steps that follow----- |
contraction
excitation-contraction coupling |
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myosin releases the ADP and phosphate and flexes into a bent, low energy position, tugging the thin filament along with it; this is called the
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power stroke
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hydrolyzing ATP and recocking
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recovery stroke
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where is pyruvic acid converted to lactic acid
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cytosol
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the break down of a glucose molecule to 2 molecules of pyruvic acis is called--------
and has a net yield of------- |
glycolysis
2 ATP |
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aerobic respiration is limited by
and produces a total of |
oxygen availibility
38 ATP per glucose molecule |
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what is the waste product of
1.anaerobic respiration---- 2. aerobic respiration------- |
1. lactic acid
2. CO2 |
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in aerobic respiration pyruvic acid enters the----------- where it is further broken down into-------
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mitochondria
CO2 and H2O |
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in glycolysis what does glucose break down to
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pyruvic acid
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what is the only advantage of anaerobic respiration
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not limited by O2 availability
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3 ways muscle cells are provided with ATP
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1. phosphagen system
2. anaerobic respiration (glycogen-lactic acid system, fermentation) 3. aerobic respiration |
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a single muscle fiber may contain--------------thick filaments.
when the fiber is contracting each filament breaks down to roughly -------------- |
15 billion thick filaments
2500 ATP molecules per second |
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which 2 systems are responsible for getting O2 out to the muscle cells
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respiratory and circulatory systems
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muscle cells store
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ATP and CP
myoglbin glycogen |
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oxygen binding pigment that give muscles tissue its reddish color
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myoglobin
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the ATP and CP stored in muscle cells are referred to as the
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phosphagen system
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polysaccharide (macromolecule composed of many glucose molecules bonded together)
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glycogen
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which system provides immediate energy
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phosphagen system
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which system provides most of the energy in sports involving intense bursts of energy lasting between 15 seconds and 1 min
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anaerobic repiration
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which system provides immediate energy for sports 15 seconds or less
football weight lifting, sprinting swim races running to 1st base ect.. |
phosphagen system
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which system provides long term energy sports where endurance rather than power is a goal jogging
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aerobic respiration
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anaerobic respiration is sometimes called
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glycogen-lactic acid system
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H2CO3
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carbonic acid
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HCO3-
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bicarbonate ions
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H+
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hydrogen ions
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creatine phosphate + ADP =
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ATP + creatine
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where is lactic acid converted back to pyruvic acid
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liver
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synergist
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a muscle that aids the prime mover, may stabilize a joint or modify direction of the movement
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antagonist
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muscle that opposes the prime mover, often maintains some tension during movement limiting the speed or range of the movement to protect injury
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fixator
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muscle that prevents bone from moving; allowing other muscles attached to it to pull on something else
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origin
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the bony site of attachment at the relatively stationary end
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insertion
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attachment site at the more mobile end
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belly
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thicker middle region of a muscle
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intrinsic muscle
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is entirely contained within a particular region having both origin and insertion there
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extrinsic muscle
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acts upon a certain region but has its origin elsewhere. the forearm muscles that control the fingers
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---------- the muscle ends short of the bone, and the gap is bridged by a fibrous band or sheet called a ---------
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indirect attachment
tendon |
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in some cases the tendon is a broad sheet called an
ex tendon beneath scalp |
aponeurosis
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in some places groups of tendons from separate muscles pass under a band of CT called a
ex the one that encircles the wrist like a bracelet |
retinaculum
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--------------the muscular tissue seems to emerge directly from the bone as seen by the naked eye, but the muscle stops short of the bone and the gap is filled by -------------
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direct (fleshy) attachment
collagen fibers |
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skeletal muscle contractions 4 overlapping functions
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1 movement
2 stability 3 control of bodies openings and passages 4 heat production- prod 85% of body heat |
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four connective tissue components from superficial to deep
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fascia
epimysium perimysium endomysium |
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CT that surrounds each muscle fiber
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endomysium
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-------thicker CT that wraps muscle fibers into bundles called---------
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perimysium
fascicles |
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fibrous sheath that surrounds the entire muscle
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epimysium
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is a sheet of CT that separates neighboring muscles or muscle groups from each other and from subcutaneous tissue
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fascia
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fascicles determine
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the strength of a muscle and the direction of its pull
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fusiform
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thick in middle and tapered at each end
ex biceps brachii |
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parellel
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fairly uniform width and parallel fascicles
ex rectus abdominis, sartorius |
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triangular (convergent)
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muscles are fan shaped, broad at origin and narrow at insertion
ex pectoralis major |
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pennate
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muscles are feather shaped, with fascicles inserting obliquely on a tendon that runs the length of the muscle
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unipennate
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muscles have fascicles approaching the tendon from 1 side
ex extensor digitorium longus |
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bipennate
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muscles have fascicles approaching the tendon from both sides
ex rectus femoris |
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multipennate
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muscles are shaped like a bunch of feathers with quills converging on a single point
ex deltoid |
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circular (sphincters)
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form rings around certain openings
ex obicularis oculi |
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the --------- of a muscle refers to the identity of the nerve that stimulates it
name the 2 general groups of nerves |
innervation
spinal nerves cranial nerves |