Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
16 Cards in this Set
- Front
- Back
|
Macrolides
ERYTHROMYCIN |
Most G+ and some G-
Respiratory and GI, sinus, skin inf. |
|
|
Erythromycin adv. effects
|
n/v/d
liver toxicity if taken with other hepatotoxic drugs (tylenol) |
|
|
Why are AIDS patients at high risk for developing TB?
|
Their compromised immune systems.
|
|
|
What are the main risks for developing drug-resistant TB?
|
Giving isoniazid only, in TB tx, multi drug tx needs to by used.
|
|
|
What are the nursing considerations regarding AIDS and TB?
|
Prophylactic therapy recommended. (HIV+ with pos TB tests = 2 month rifampin and pyrazinamide)
|
|
|
Who should be given INH?
|
Persons who have been in close contact with those with TB, HIV+ pts with a +TB test.
|
|
|
What adverse effects does INH have?
|
Can cause liver damage
|
|
|
Why is active, symptomatic TB always treated with multiple drugs?
|
Resistance did not occur and treatment time was reduced from 2 yrs to 6-9 months
|
|
|
What are the adverse effects of INH; rifampin
|
INH: peripheral neuropathy, hepatotoxicity. Rifampin: increased liver enzyme levels.
|
|
|
What are the adverse effects of pyrazinamide; ethambutol?
|
renal insufficancy
|
|
|
What are the clinical indications for the use of acyclovir and zidovudine?
|
Acylovir - herpes, zidovudine (AZT) - HIV mgmt
|
|
|
How do AZT, didanoside, dideoxycytidine act against HIV?
|
nucleoside reverse transcriptase inhibitors, suppress viral erplication to slow decline in the number of CD4+ cells, reduce incidence and severity of opportunistic infections
|
|
|
Major adverse effects of AIDS drugs?
|
lactic acidosis, hepatomegaly, hyperglycemia, increased bleeding.
|
|
|
What are the clinical indications for the use of acyclovir and zidovudine?
|
clients of symptoms of clinical AIDS (opportunistic infection) or immunologic AIDS (CD4+ count <200), also asymptomatic clients with a count less than 350 but viral load over 55K
|
|
|
What is a retroviral drug?
|
one that suppresses a retrovirus such as HIV
|
|
|
What is a protease inhibitor?
|
antiretroviral (Kaletra) block protease -keeps virus from replicating
|
