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29 Cards in this Set

  • Front
  • Back

4 types of chemoreceptors

1.taste receptors


2. olfactory receptors


3. visceral chemoreceptors


4.chemosensitive endings


- have warning and reward fx

visceral chemoreceptors

detect O2, glucose, hormone levels, etc for homeostasis, monitor internal environment

chemosensitive endings

mediate common chemical sense- heat of chili peppers, cool of menthol, sting of amonia

taste

detection of chemicals in water solution. chemical detection of sweet, salty, sour, bitter and savory (umami)

flavor

the combination of smell, taste and common chemical sense (pungency, spiciness) and somatosensory (temp and texture)

papillae

bumps and folds of tongue, 3 types


1. fungiform


2. foliate


3. vallate or (circumvallate)

fungifrom papillae

located at the tip and sides of tongue


CN III


each contain 3-5 taste buds

foliate papillae

located on posterior and sides of tongue


CN VII and IX

vallate papillae

-series of 8 or 9 papillae arranged in a V shape on the post 1/3 of tongue


- CN IX


-each contain about 250 taste buds

taste buds

modified spindle shaped epithelial cells with neuron like properties.


-lifespan of a couple weeks


 

how tastebud work?

microvilli processes extend thru a tastepore, here they are exposed to the chemical stimuli dissolved in the saliva, which produce receptor potentials. chemical synapses are made on the end of cranial nerves.

sweet

sugars, saccharin, alcohol, and some amino acids

sour

H+

salt

metal ions

bitter

alkaloids such as quinine and nicotine

umami

savory - like grilled meat. aminoacids glutamate (MSG) and aspartate

salt transduction

cation channels in tastebuds allow Na+ influx which depolarizes the cell.  influx Na+  correlates directly to amount of Na+ in saliva

sour transduction

usually due to acids (H+)


- open pH sensitive cation channels  and cause depolarization

sweet, bitter and umami

G-coupled protein channels cause cation channels to open and the cell to depolarize

taste pathway

tastebuds synapse onto cranial nerves--> solitary tract--> solitary nucleus-->B/L to VPM of thalmus-->I/L gustatory cortex in the insula

smell

-detection of airborn chemicals


-peripheral receptors in olfactory epithelium in roof of nasal cavity


-innervated by CN I


-CN V in olfactory epithelium for common chemical sense e.g. amonia

olfactory receptors

-true bipolar neurons


-odors are caught in a layer of mucus via cilliary hairs  which are teh olfactory vessicle


 

pathway for smell

olfactory vesicle (dendritic end on receptor cell lives in snot)-->receptor cells in olfactory epithelium-->unmylinated axons collect into olfactory filia-->filia pass thru holes in the olfactory plate  that synapse with the olfactory bulb (the first CN)

smell transduction

-binding of oderatant causes cation channels to open and depolarization, if local potential is high enough AP are sent.  the cells quickly adapt to prolonged stimuli

olfactory pathway post endering bulb

olfactory nerves --> lateral olfactory tracts--> to uncus --> 1* olfactory cortex (& amygdala)--> DM--> olfactory association area (in frontal lobe/insula next to the gustatory cortex)--> many places

ansomnia

loss of smell

conductive deficits

-blockage of nasal cavity/ olfactory epithelia


-causes include septal deviations,  nasal polyps, inflammation and allergies

sensorineural deificts

-damage to neural components


-usually due to head injuries where nerve is damaged at the cribiform plate


-or neurodegenerative diseases like parkinson's or alzheimers

seizure in uncus

-can cause olfactory hallucinations and behaviors like smacking lips