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18 Cards in this Set
- Front
- Back
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acid
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molecule that can liberate H+ ions and thus can raise H+ ion [ ] of aqueous solution above that of pure water
strong acid- acids that tend to give up H+ (ionize) more completely |
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base
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molecule capable of combining with H+ ions therefore lowers H+ ion [ ] of solution
strong bases-bases that ionize completely |
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pH
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negative log of H+ ion [ ]
= -log10 [H+] |
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acidosis
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as H+ ion [ ] increases pH declines and acidity of blood increases
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alkalosis
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as H+ [ ] decreases pH increases and solution becomes more basic
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normal resting pH of arterial blood
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7.4 in health (varies 0.05
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survival range
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6.8-7.8
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sources of H+ ions during exercise:
volaltile |
CO2 an end product in oxidation of carbohydrates, fats, and proteins can be regarded as as acid by virtue of its ability to react with water to form carbonic acid (H2CO3) dissociates to H+ and HCO3-
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sources of H+ ions during exercise:
organic |
lactic acid and acetoacetic acid are formed in metabolism of carbs and fats respectively
normal- these acids are further metab into CO2, dont greatly influence pH of body fluids intense-skeletal muscles produce large amounts of lactic acid resulting in acidosis heavy-greatest challenge to maintain pH homeo during exercise |
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sources of H+ ions during exercise:
fixed |
sulfuric acid is a product of the oxidation of certain amino acids while phosphoric acid is formed in the metabolism of various phospholipids and nucleic acids
not influenced by acute exercise not major contributors of H+ ions during heavy exercise |
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how does pH change with exercise
difference between blood and muscle |
????
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intracellular buffering systems
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most common: proteins, phosphate groups, and bicarbonate
-contain ionizable groups that are weakacids capable of accepting H+ions |
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extracelluar buffering systems
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three principal buffer systems: hemoglobin, bicarbonate, and blood proteins
weak acids that can act as buffers |
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changes in lactate during exerice
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?
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changes in bicarbonate during exerice
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?
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changes in pH during exerice
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?
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role of lungs in pH regulation
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?
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role of kidneys in pH regulation
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?
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