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18 Cards in this Set
- Front
- Back
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cerebellum function
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coordinate voluntary motor and cognitive output with sensory feedback
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spinocerebellum
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-anterior lobe + vermis
-postural reflexes/equilibrium |
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vestibulocerebellum
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-flocculus and nodule
-equilibrium and anti-gravity muscles |
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pontocerebellum
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posterior lobe
-voluntary movement and smoothing of motion |
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cerebellar dysfunction signs
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disequilibrium, ataxia, dysmetria, abnormal tone, intention tremor
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cerebellar architecture
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3 layers:
granule cell layer purkinje cell layer molecular layer |
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granule cells
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-found in granule cell layer
-excitatory -send axons to the molecular layer -axons branch into parallel fibers |
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purkinje cells
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-send dendrites into the molecular layer
-project to deep cerebellar nuclei -GABAergic |
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stellate cells
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star shaped inhibitory interneurons of the molecular layer
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basket cells
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interneuron: axosomatic inhibition in the molecular layer
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golgi cell
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-@the border of the purkinje and granule cell layers
-form inhibitory axoaxonic synapses on mossy fibers |
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climbing fibers
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-originate in the inferior olive
-excite purkinje cells |
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mossy fibers
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-form excitatory mossy terminals in the granule cell layer
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cerebellar output
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arises mostly from the 4 deep nuclei but there are also direct purkinje cell projections to the lateral vestibular nucleus
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fastigial nucleus pathway
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vestibular apparatus, and vestibular nuclei--(ICP)-->flocculo-nodular lobe mossy fibers-->fastigial nucleus-->vestibular nuclei
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globose and emboliform pathway
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proprioceptive: nucleus dorsalis, external cuneate nucleus (via ICP), and ventral spinocerebellar tract (via SCP)--> anterior lobe/vermis mossy fibers
corollary motor: red nucleus-->inf. olive--(crosses)-->climbing fibers of anterior lobe/vermis anterior lobe and vermis=> globose and emboliform--(SCP)--> contralateral red nucleus |
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dentate pathway
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exteroceptive: cerebral cortex and corollary motor: corticospinal tract-->pontine nuclei--(MCP)-->contralateral posterior lobe--> dentate nucleus--(SCP)-->contralateral VL
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'higher' cerebellar functions
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role in classical conditioning, concentration, word selection, learning and performing complex motor tasks, emotionality (ie. 'though coordination')
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