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14 Cards in this Set
- Front
- Back
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Five (generations) |
Generations of cephalosporins currently established |
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First (1st gen) |
Generation of cephalosporins that has activity only for G(+) |
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Cefazolin |
Drug of choice for surgical prophylaxis |
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Cefazolin |
The only first generation cephalosporins that can be administered intravenously |
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Second (2nd gen) |
Generation of cephalosporins that has extended G(-) activity but not on Pseudomonas and Enterococci |
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Cefuroxime |
The only second generation cephalosporin that can cross the BBB but has no effect on meningitis |
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Third (3rd gen) |
The generation of cephalosporins that has more G(-) activity including Pseudomonas |
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Ceftazidime, cefoperazone |
Two third gen cephalosporins for pseudomonas only |
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Cefoperazone, ceftriaxone |
Two 3rd gen cephalosporins excreted biliary |
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Cefepime |
4th gen cephalosporin that's more resistant to beta-lactamases and penetrates the BBB |
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Ceftaroline |
5th gen cephalosporin with activity against MRSA |
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Cefamandole, Cefmetazole, Cefotetan |
Three 2nd gen cephalosporins that produce Hypoprothrombinemia as an adverse effect |
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Hypoprothrombinemia |
3rd gen cefoperazone produces this adverse effect together with 3 other 2nd gen cephalosporins |
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Cefamandole, cefmetazole, cefotetan, cefoperazone |
Four cephalosporins that produce disulfiram-like reaction in the presence of alcohol |
