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3 Cards in this Set
- Front
- Back
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Rolling
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Selectin molecules form WEAK bonds with the Integrin molecules found on the surface endothelium of blood vessels.
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Adhesion
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LFA-1 (A β-2 Integrin) on the Leukocytes binds with the ICAM-1 molecules (Ig family) on the Endothelial surface due to an increased affinity.
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Diapedesis
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Transmigration of immune cells accross endothelia. Mediated by PECAM-1/CD-31. Enzyme collagenase breaks down basement membrane.
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