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73 Cards in this Set

  • Front
  • Back

Cytology

The study of cells
Cell
Basic unit of life. Shows life characteristics such as organization, metabolism, responsiveness, homeostasis, growth, & reproduction.
General cell organization
Plasma
Nucleus
Cytoplasm
-Cytosol
-Organelles
Plasma Membrane
Encloses cell contents. Regulates what enters & leaves cell.
Components of Plasma membrane
-Phospholipid bilayer (main component)
-Cholesterol
-Proteins
Channels
Pores in plasma membrane that allow passage of specific substances.
Transporters
Shuttle substances across membrane

Receptors

Allow for attachment of substances to membrane; used for cell-to-cell signaling

Enzymes

Participate in chemical reactions at membrane surface

Linkers

Give structure to membrane and attach cells to other cells

Cell Identity Markers

Proteins unique to a person's cells; important for immunity

Membrane potential

The difference in electric charge on either side of the plasma membrane.


caused by separation of positive and negative ions and proteins on either side of the membrane. Ions determined by channels & pumps. Allows plasma membrane to act as a battery.

Nucleus

Largest organelle, surrounded by nuclear membrane, contains chromosomes and nucleolus.

Cytoplasm

Material between nuclear membrane and plasma membrane.

Cytosol

Fluid portion of cytoplasm

Organalles

Specialized cell structures that perform different cell functions.

Endoplasmic Reticulum

Membranous network, only rough ER has ribosome, smooth has no ribosomes.


Rough ER sorts and modifies proteins, smooth ER synthesizes lipids.

Ribosomes

Small bodies in cytoplasm or attached to rough ER. Manufactures proteins.

Mitochondria

Large bodies with internal folded membranes. Manufactures ATP.

Golgi Apparatus

Layers of membranous sacs. Prepares proteins for export.

Lysosomes, Peroxisomes

Small sacs of enzymes. Digests intracellular substances. Detoxify, stabilize free radicals.

Vesicles

Small storage sacs. Store materials, move materials into or out of cell.

Centrioles

Rod-shaped near nucleus. Separate chromosomes during cell division.

Cilia

Short hairlike projections that move fluids around cells

Flagellum

Long, whiplike extension from the cell. Moves the cell. Ex: sperm

Microvilli

Small projections of plasma membrane. Increase surface area. Ex: cells in small intestines that allow for absorption.

Cell Diversity

Cell shape is related to its function. A neurons long fibers transmit electric energy from place to place in the nervous system.


cell organelle # is related to its function. Lipid producing cells have lots of smooth ER, metabolically active cells have lots of mitochondria to manufacture ATP.

Selective permeability

Plasma membrane regulates what enters and leaves.


Based on several factors:


molecular size, solubility, & electrical charge

Passive transport

Movement that does not require cellular energy

Active transport

Movement that requires cellular energy. Needs ATP to make anything happen. Solute moves through plasma membrane against its concentration gradient with help of transporters

Diffusion

Solute travels across plasma membrane down its concentration gradient

Facilitated diffusion

Solute diffuses with help of a transporter

Osmosis

Solvent travels across plasma membrane down its concentration gradient.


"water follows salt!"

Filtration

Mechanical force pushes solute and solvent across plasma membrane

Concentration gradient

The measurable difference in concentration between one solution and another

Isotonic

Has same solute concentration as cell

Hypotonic

Has lower solute concentration than cell

Hypertonic

Has higher solute concentration than cell

Aquaporis

Pores where water enters and leaves cell

Endocytosis

Large amounts of solute and solvent are transported into cell using vesicles

Exocytosis

Large amounts of solute and solvent are transported out of the cell using vesicles.

Phagocytosis

Engulfing a solid particle, "cell eating"

Pinocytosis

Engulfing a liquid particle, "cell drinking"

Protein synthesis

Proteins give a cell its structure and function. The body has many uses for proteins - components of cells, material to build muscle, bone and connective tissues, pigments for hair, eye and skin color, enzymes, hormones, antibodies. Cells make the bodies proteins.

2 Organic compounds known as nucleic acids

Deoxyribonucleic Acid (DNA)


Ribonucleic Acid (RNA)

DNA & RNA

Carry genetic information, work together to guide cells in building proteins. Both are composed of subunits called nucleotides

Nucleotides

made up of a sugar unit, a phosphate unit, and I nitrogen base.

Nitrogen bases in DNA nucleotides

(A) adenine


(T) thymine


(G) guanine


(C) cytosine


A with T, G with C

Nitrogen bases in RNA nucleotides

(A) adenine


(U) uracil


(G) guanine


(C) cytosine


A with U, G with C

DNA molecule

Latter-like double strand of nucleotides known as a double helix. Latter uprights are sugar & phosphate, rungs are nitrogen bases. Makes up chromosomes, divided into gene, carries nucleotide codes for protein synthesis.

RNA molecule

Single strand of nucleotides, 3 types mRNA, rRNA, & tRNA. Manufacture proteins according to the DNA code.

Chromatin

long, slender threads of DNA in the nucleus of a cell, condensed into chromosomes during cell division.

Chromosomes

Hereditary unit. All human cells but egg/sperm cells have 46. Each is broken down into subunits called genes.

Genes

subunits of chromosomes, a segment of DNA that contains instructions for building one protein.

mRNA

Messenger RNA, is built on a strand of DNA in the nucleus and transcribes the nucleotide code. Moves to cytoplasm and attaches to a ribosome.

rRNA

Ribosomal RNA, with protein makes up the ribosomes, the sites of protein synthesis in the cytoplasm. Involved in the process of translating the genetic message into a protein.

tRNA

Works with mRNA & rRNA to translate the genetic code into protein. Each molecule of tRNA carries an amino acid that can be used to build a protein at the ribosome. Composed of 3 nucleotides and an amino acids.

Transcription

Information transferred from DNA to RNA, takes place in nucleus when double stands of DNA are split, a new molecule of RNA is built alongside the strand of DNA

Triplet

A group of 3 nucleotides in DNA; each corresponds with a specific amino acid.

Codon

A group of 3 nucleotides in the new RNA molecule; the complement to the triplet.

Translation

The nucleotide sequence of the mRNA is decoded to build a protein. In the cytoplasm, a ribosome (composed of ribosomal RNA or rRNA) attaches to the mRNA. Ribosome guides the interaction between mRNA and tRNA.

Anticodon

The 3 nucleotides of tRNA; complementary to the codon carried by the mRNA.

Cell division

Allows the body to grow, repair itself and reproduce. 2 types: meiosis & mitosis

Meiosis

Produces egg & sperm cells, cuts chromosomal number in half.

Mitosis

Produces somatic (body) cells, produces 2 identical daughter cells.

Interphase

Period of time between one mitosis and the next; DNA replicates during this phase. Typical cell is in this phase most of the time.

What are the 2 new identical DNA strands held together by before cell division?

Centromere

Prophase

DNA strand coils into chromosomes, nucleolus and nuclear membrane disappear, & centrioles move to opposite poles and form spindle.

Metaphase

Chromosomes line up across center of cell, chromosomes attach to spindle.

Anaphase

Centromeres split, make chromosomes move towards opposite centrioles.

Telophase

chromosomes continue to move toward centrioles, nuclear membrane forms around each group of chromosomes, cytokinesis.

Cytokinesis

Plasma membrane pinches off in middle of cell to form 2 new identical daughter cells.

Apoptosis

Organized cell death.