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20 Cards in this Set
- Front
- Back
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What are the functions of intermediate filaments?
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Sturctural integrity of the cells
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What are 3 examples of intermediate filaments and the tissue they're associated with?
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1. Vimentin-mesenchymal
2. Keratin-epithelial 3. Desmin-muscle |
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What are the 6 different categories cell types are generally categorized into?
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1. Nerve
2. Muscle 3. Blood 4. Lymphoid 5. Epithelial 6. Connective |
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What are 3 functions of epithelial tissue?
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1. Barrier function
2. Exchange of nutrients, mucous between environments 3. Surfactant secretion in gas exchange in alveoli |
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What is the function of a tight junction?
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Seals neighboring cells together in an epithelial sheet to prevent leakage of molecules between them.
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What is the function of adherens junction?
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Joins an actin bundle in one cell to a similar bundle in a neighboring cell.
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What is the function of a desmosome?
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Joins the intermediate filaments in one cell to those in a neighbor.
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What is the function of a gap junction?
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Allows the passage of small water-soluble ions and molecules.
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What is the function of a hemidesmosome?
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Anchors intermediate filaments in a cell to the basal lamina.
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What are the types of interactions between proteins connecting cells together?
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1. Homophilic
2. Heterophilic 3. Binding through an extracellular linker molecule |
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What type of interaction is a tight junction an example of?
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Homophilic
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T/F Claudins are transmembrane proteins that combine with occludens and junctional adhesion molecules?
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True
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What are two main functions of tight junctions?
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1. Barrier (Gate)-controls passage of molecules from extracellular environment
2. Fence-seperates proteins on apical side of membrane from those on the basal-lateral side. |
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T/F Other types of cell junctions occlude small molecules?
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False, only tight junctions. That is why they are also known as zona occludens.
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T/F If you remove calcium, tight junctions fall apart?
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True, certain pathogens control calcium in external media and can also go inbetween cells.
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What type of interaction is a tight junction an example of?
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Homophilic
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T/F Claudins are transmembrane proteins that combine with occludens and junctional adhesion molecules?
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True
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What are two main functions of tight junctions?
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1. Barrier (Gate)-controls passage of molecules from extracellular environment
2. Fence-seperates proteins on apical side of membrane from those on the basal-lateral side. |
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T/F Other types of cell junctions occlude small molecules?
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False, only tight junctions. That is why they are also known as zona occludens.
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T/F If you remove calcium, tight junctions fall apart?
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True, certain pathogens control calcium in external media and can also go inbetween cells.
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