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5 Cards in this Set

  • Front
  • Back
Functions of the cytoskeleton
-movement of organelles
-shape
-motility
Filiments of cytoskeleton & nucleus
-intermediate
-microtubules
-microfiliments
Intermediate filiments
-mechanical strength
-used to find tissues of origin i.e. mets
keratins:epi
desmin:muscle
neurofiliments:neurons
vinmentin:fibroblasts,chondroblasts
lamins:nuclear lamina
Microtubules
-position of organelles/direct intracellular transport
-GTP binds to + end of alpha & beta tubulin dimer shrinks & lenghtens
-assoc. w/ kinesin (long)moves stuff to + end & dynein(short) - end =>movement
- in mtoc
i.e. cillia w/ basal bodies 9+2 arrangement
Microfiliments
- aka F actin
-made of G actin binds to ATP= shortening
-@ PM
-has 2 actin crosslinking prot.:alpha actinin,fimbrin
-has 2 actin binding prot.: spectrin,myosin