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24 Cards in this Set
- Front
- Back
Genotyping |
Determining genetic differences between individuals by using markers |
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Chromosome Painting |
Probes bind to specific sequences on specific chromosomes allowing detection |
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FISH |
Fluorescent In Situ Hybridization |
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Percentage of embryos with chromosomal abnormalities from normal parents |
10% |
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When does most embryo loss occur? |
First 16 days of development |
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Fertilization efficiency and percentage of fertilizations leading to calves |
80% 30-50% |
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Nondisjunction definition and when most common |
Failure of chromosomes pairs to seperate Mieosis |
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Pseudoautosomal Regions |
Areas where X and Y chromosomes pair up and can undergo homologous recombination |
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2 reasons each gamete is unique |
1) Homologous recombination 2)Independent segregation |
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Synaptonemal Complex |
Protein holding paired chromosomes together at the synapsis during meiosis I |
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Pyrimidines |
Thymine Cytosine |
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Purines |
Adenine Guanine |
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DNA -->Chromosome organization |
DNA wraps around histones forming nucleosome which then forms solenoid |
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Method used to sort chromosomes for karyotype |
Banding Pattern -Giemsa Stain then sorted |
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Severe Combined Immunodeficiency |
DNA Protein Kinase deficit that prevents lymphocyte maturation increasing disease susceptibility Found in Arabian horses |
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Von Willebrand's Disease |
Defect in VWF leading to prolonged bleeding Doberman |
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Non neoplastic growth Disturbances (4) |
Hyperplasia (increase in cell number) Hypertrophy (increase in cell size) Atrophy (decrease in cell size or number) Hypoplasia (failure to develop normally) |
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Characteristics of Acute Inflammation (5) |
Redness Heat Swelling Pain Loss of Function |
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Types of vascular disorders (5) |
Blood coagulation defect Blood vessel injury Blood vessel obstruction Circulatory Failure Thrombosis |
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Oncosis |
Passive cell death due to inability to maintain homeostasis |
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Apoptosis |
Active process of cell mediated cell death |
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Necrosis and Processes (2) |
Irreversible Apoptosis Oncosis |
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Cell degeneration |
Reversible damage |
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Disease processes (6) |
Cell Injury Cell and tissue accumulations Vascular disorders Inflammation and repair Neoplastic growth non neoplastic growth |