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24 Cards in this Set

  • Front
  • Back

Genotyping

Determining genetic differences between individuals by using markers

Chromosome Painting

Probes bind to specific sequences on specific chromosomes allowing detection

FISH

Fluorescent In Situ Hybridization

Percentage of embryos with chromosomal abnormalities from normal parents

10%

When does most embryo loss occur?

First 16 days of development

Fertilization efficiency and percentage of fertilizations leading to calves

80%


30-50%

Nondisjunction definition and when most common

Failure of chromosomes pairs to seperate


Mieosis

Pseudoautosomal Regions

Areas where X and Y chromosomes pair up and can undergo homologous recombination

2 reasons each gamete is unique

1) Homologous recombination


2)Independent segregation

Synaptonemal Complex

Protein holding paired chromosomes together at the synapsis during meiosis I

Pyrimidines

Thymine


Cytosine

Purines

Adenine


Guanine

DNA -->Chromosome organization

DNA wraps around histones forming nucleosome which then forms solenoid

Method used to sort chromosomes for karyotype

Banding Pattern


-Giemsa Stain then sorted

Severe Combined Immunodeficiency

DNA Protein Kinase deficit that prevents lymphocyte maturation increasing disease susceptibility


Found in Arabian horses

Von Willebrand's Disease

Defect in VWF leading to prolonged bleeding


Doberman

Non neoplastic growth Disturbances


(4)

Hyperplasia (increase in cell number)


Hypertrophy (increase in cell size)


Atrophy (decrease in cell size or number)


Hypoplasia (failure to develop normally)

Characteristics of Acute Inflammation


(5)

Redness


Heat


Swelling


Pain


Loss of Function

Types of vascular disorders


(5)

Blood coagulation defect


Blood vessel injury


Blood vessel obstruction


Circulatory Failure


Thrombosis

Oncosis

Passive cell death due to inability to maintain homeostasis

Apoptosis

Active process of cell mediated cell death

Necrosis and Processes (2)

Irreversible


Apoptosis


Oncosis

Cell degeneration

Reversible damage

Disease processes


(6)

Cell Injury


Cell and tissue accumulations


Vascular disorders


Inflammation and repair


Neoplastic growth


non neoplastic growth