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12 Cards in this Set
- Front
- Back
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Celo mediated responses are mediated by which cells?
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T cells
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Where are T cells produced and where do they mature?
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Bone Marrow
Mature in thymus gland |
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Self antigen MHC1 molecules are expressed with cells with a nucleus that are infected by what?
They are considered what type of antigens? |
A virus
Endogenous |
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There are 3 different complexes of MHC1 molecules which are?
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HLA-A
HLA-B HLA-C Human Leukocyte Antigen (ABC) |
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MHCII molecules have which kind of antigens and Why
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Exogenous
They engulg antigens that are not native to the body |
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MHCII molecues are typed?
What is the classificaton derived from? These molecules are also known as? |
HLA-DP
HLA-DQ HLA-DR The Gene that forms them Antigen presenting cells |
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How does a MHCII molecule digest an antiegn?
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By engulfing it in the phagosome inside the cell
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What the main types of antigen presenting cells?
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Macrohages
dendritic cells B cells |
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What are macrohages pre-cursor and where are they found?
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Monocytes
connective tissue, lymphatic tssue and extravascular spaces |
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Macrohpages present the MHCII + antigens to which cell?
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helper T cells
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Macrohpages secrete which Interleuckin and what does it promote?
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IL-1 and promotes secretion of IL-2 from helper T cells
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What does IL-2 do to helper T cells?
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Promotes the division an dproliferation of helper T cells
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