Cell Injury

Front 1

1. A localized lesion charac. By necrotic, liquefied center, polymorphonecular leukocytes and microorganisms is called

Back 1

abscess

Front 2

2. A circumscribed mass of light yellow crumbly to pasty material assoc. microscopically with a histiocytic reactino is characteristic of

Back 2

caseous

Front 3

3. A myocardial infarct is a good example of

Back 3

coagulation

Front 4

4. A well-demarcated lesion with increased cytoplasmic eosinophilia, karyolysis and intact tissue architecture is a characteristic of

Back 4

coagulation

Front 5

5. All of the following are examples of reversible cell injury: fatty liver of an alchoholic, swelling of renal tubular cells in lead poisoning, and accumulation of amyloid in the liver. What is not?

Back 5

coagulation in infarcted myocardium

Front 6

6. Superoxide dismutase, glutathione peroxidase, xanthine oxidase, and ceruloplasmin all have anti oxidant action What does NOT?

Back 6

xanthine oxidase

Front 7

7. Anoxia can lead to each of the following changes in a cell: nuclear pknosis, fatty change, amyloid deposition, and cytoplasmic eosinophilia. NOT

Back 7

amyloid deposition

Front 8

is best described as granular, friable mass of material with no cell outlines

Back 8

caseous

Front 9

is characterized morphologically by amorphous appearence

Back 9

caseous

Front 10

is most characteristic of tuberculosis

Back 10

caseous

Front 11

is usually associated with tuberculosis

Back 11

caseous

Front 12

12. Cell swelling in acute tubular necrosis of the kidney is caused by intracellular accumulation of

Back 12

water

Front 13

13. Cells which are least affected by generalized energy deprivation such as occurs in starvation are

Back 13

fat cells

Front 14

14. Cloudy swelling, hydropic degeneration and vacuolar degeneration are all examples of

Back 14

morphologic expression of reversible cell injury

Front 15

is best described as eosinophilic cytoplasm with cell outlines preserved.

Back 15

coagulation

Front 16

is the characteristic result of renal infarction

Back 16

coagulation

Front 17

17. Coagulation necrosis may be caused by

Back 17

by both ischemia without vascular obstruction or toxic chemicals.

Front 18

18. Coagulation necrosis usually results from

Back 18

ischemia

Front 19

19. Digestion of tissue with soap formation and calcification is characteristic of

Back 19

enzymatic fat necrosis

Front 20

20. Dry gangrene is best described microscopically by

Back 20

coagulative

Front 21

21. coagulation, enzymatic fat and liquefacation necrosis can be identified on basis of gross appearance. What can't?

Back 21

fibrinoid

Front 22

22. Enzymatic fat necrosis is assoicated with each of the following:trauma to subcut. Adipose tissue, acute pancreatic necrosis, breakdown of tg esters, inflammatory reaction. NOT

Back 22

trauma to subcutaneous adipose tissue

Front 23

23. Enzymatic fat necrosis occurs in the

Back 23

pancreas

Front 24

24. Examples of necrotic lesions which heal by fibrous scarring: myocardial infarct, abscess in lung, kidney infarct, caseous nodules in lymph node. NOT

Back 24

tubular necrosis in the kidney.

Front 25

is seen in blood vessels due to accumulation of Igs and complements.

Back 25

Fibrinoid necrosis

Front 26

26. Free radical injury has been implicated in patients with oxygen toxicity, carbon tetracholride poisoning, reperfusion following ischemia, irridation injury. Not

Back 26

mercuric chloride poisoning

Front 27

27. Gas gangrene is a form of necrosis assoc. with mycotic infections

Back 27

clostridial infections

Front 28

28. Gummas are associated with

Back 28

tertiary syphilis

Front 29

29. Homogenous eosinophilic protein inclusions in the ER of plasma cells are called

Back 29

Russel bodies

Front 30

30. Lipid peroxidation with generation of free radicals has been implicated in the cellular change due to: aging, carbon tetrachloride and ionizing radiation. Not

Back 30

complement

Front 31

necrosis charactistically occurs in both brain infarct and kidney abscess.

Back 31

liquefaction

Front 32

is characteristic of abscesses in the liver

Back 32

liquefaction

Front 33

usually occurs with infarction of the brain

Back 33

liquefaction

Front 34

34. Necrosis in brain infarcts is characterized by

Back 34

coagulation necrosis in the early phase

Front 35

35. Occlusion of the right coronary artery near its origin would most likely result in infarction of

Back 35

anterior septum

Front 36

most characteristically causes coagulation necrosis

Back 36

obstruction of blood flow

Front 37

37. The action of putrefactive bacteria on necrotic tissue results in

Back 37

gangrene

Front 38

38. The earliest visible cellular change in a cell injured by hypoxia is

Back 38

cellular edema

Front 39

39. The major free radical generated by Fenton and Haber-Weiss reaction is:

Back 39

hydroxyl radical

Front 40

40. The pattern of necrosis assoc. with staph infection with the formatin of furuncles is

Back 40

liquefaction

Front 41

41. The pattern of necrosis assoc. with the cell-mediated immune response is

Back 41

caseous

Front 42

42. The pattern of cell death that is characterized by conversion of a single cell to a shrunken acidophilic body usually with loss of the nucleus and lack of an inflammatory response is termed

Back 42

apoptosis

Front 43

43. Type of necrosis assoc. with a well developed infarct of the brain is

Back 43

liquefaction

Front 44

Type of necrosis char. in burn injury

Back 44

liquefaction

Front 45

45. Type of necrosis resulting from saprophytic invasion of tissue dying from ischemia is called

Back 45

gangrenous

Front 46

46. Vascular obstruction is a cause of ___ not____

Back 46

coagulation necrosis NOT caseous necrosis

Front 47

47. Vascular occlusion is the most common cause of

Back 47

coagulation necrosis and dry gangrene.

Front 48

48. What is the outcome of a 1cm caseous lesion after treatment

Back 48

scarring and calcification

Front 49

49. What type of necrosis results from programmed destruction of cells during embryogenesis?

Back 49

Apoptosis

Front 50

_____are reversible. Pknosis, rupture of cell membrane, karyolysis, karyorrhexis are NOT.

Back 50

cytoplasmic vacuoles

Front 51

51. Which of the following deposits are removed during the preparation of paraffin embedded tissure sections?

Back 51

cholesterol

Front 52

52. Which of the following is indicative of reversible cell injury?

Back 52

Dispersion of ribosomes from RER. Karyorrhexis, Rupture of lysosomes and autolysis, high swell of mitochondria and large flocculent densities in the mitochondria are NOT

Front 53

53. Which of the followig is the earliest nuclear change seen by light microscopy in dying cells

Back 53

Pyknosis

Front 54

54. Which tissure is most susceptible to liquefaction necrosis following ischemic injury?

Back 54

Brain

Front 55

55. Which type of necrosis is most typically associated with pyogenic infection?

Back 55

Liquefaction