Cell Cycle

Front 1

Stages of the cell cycle

Back 1

G1
S
G2
M
Go

Front 2

Go

Back 2

The cell enters this stage when it stops dividing
Degrades cdk's
some cells spend all their time there and some never enter it

Front 3

Quinescence

Back 3

Stops dividing but can be induced with high levels of growth factors to reenter the cell cycle

Front 4

Senescence

Back 4

stops dividing and cannot be induced to reenter the cell cycle

Front 5

G2 checkpoint

Back 5

is DNA replicated, is environment favorable

Front 6

Metaphase checkpoint

Back 6

Are all the chromosomes alligned

Front 7

G1 checkpoint

Back 7

is the environment favorable,must have a growth factor

Front 8

G1/S cyclin

Back 8

expressed in G1 acts on G1/S cdk

Front 9

S cyclin

Back 9

acts on S cdk and acts in S phase

Front 10

M cyclin

Back 10

acts on M cdk and starts to rise in G2 but ends half way through Mphase

Front 11

Wee1

Back 11

a kinase that phosphorylase and inactivates the Cdk
puts a phosphate on in addition to the one put on by CAK

Front 12

Cdc25

Back 12

a nonspecific Cdk phosphatase that takes off the inactivating phosphate put on by Wee1 and activates Cdk's

Front 13

CAK

Back 13

Cdk activating kinase puts on the first activating kinase by putting a phosphate on the Cdk

Front 14

SCF-

Back 14

degrades S cyclin

Front 15

SRC

Back 15

give tyrosine kinase signal without a mitogen