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43 Cards in this Set

  • Front
  • Back
What is the definition of Metabolism?
All chemical Reactions in a Cell
What are the two types of reactions in Metabolism?
Anabolic Reactions and Catabolic Reactions
Which type of reaction in Metabolism is responsible for synthesizing cellular components and is an endergonic reaction?
Anabolic Reactions
Which type of reaction in Metabolism is responsible for breakdown and is an exergonic reaction?
Catabolic Reactions
Which type of pathway (reaction) in metabolism involves a substantial increase in molecular order?
Anabolic
Which type of pathway (reaction) in metabolism involves an increase in entropy and a negative free energy?
Catabolic
The Roles of This Metabolic Pathway:
1.) release the free energy needed to drive cellular functions.
2.) Give rise to small organic molecules, or metabolites, that are the building blocks for biosynthesis
Catabolic pathway
Known as the universal energy coupler
ATP
How much free energy is released When ATP is broken down by Catabolism?
-7.3 kcal/mol
This type of metabolic pathway is responsible for driving the anabolic reactions and carrying out other kinds of cellular work
Cataboic Pathway
In the synthesis of ATP, What is the first step?
Substrate level Phosphorylation
What happens in substrate level phosphorylation?
An inorganic phosphate group and ADP combine to form ATP
What is the second step in ATP synthesis?
Oxidative Phosphorylation
These 3 steps are known as __________, a step in ATP synthesis
a.) Source of electrons at high energy level
b.) Sugars/Lipids: Electron Transport system-in a membrane
c.) Build H+ gradient across that membrane
Oxidative Phosphorylation
This allows the high concentration of H+ outide the cell to re-enter back into the cell
H+ transport protein
In Oxidative Phosphorylation ATP is produced because of...
The facilitated diffusion of H+ across the membrane
The facilitated diffusion of H+ back into the cell has a negative or positive change in free energy? Endergonic or Exergonic?
Negative; Exergonic
In Glycolysis of Glucose what is produced when 6 carbon Glucose is made into 2 pyruvate (3 Carbon)?
NADH and a little ATP
In the break down of glucose, What does the 2 pyruvate (3C) produce when it makes Acetyl Co A (2C)?
NADH and 2 CO2
How does the process of Krebs cycle make a 4 carbon molecule (starting material) into a 6 carbon molecule in 2 cycles?
The acetyl Co A (2C) combine with the 4 carbon material to make a 6 carbon molecule
In the Krebs Cycle, What is produced when The 6 carbon molecule becomes a 5 carbon molecule?
CO2 and NADH
In the Krebs Cycle, What is produced when The 5 Carbon molecule becomes a 4 carbon molecule?
CO2 and NADH
In the Krebs Cycle, When the 4 carbon molecule is further oxidized, what is produced?
FADH2 and NADH
After The krebs cycle, all the NADH and FADH2 enter the _______ _______ _______
electron transport chain
What is the key carrier to electron transport chain and what is the full name of this carrier?
NAD+ . Nicotinamide Adenine Dinucleotide
In they glycolytic pathway from glucose to pyruvate, What is the first step?
Glucose is converted to Glucose-6-Phosphate by the input of ATP and the release of ADP
In they glycolytic pathway from glucose to pyruvate, how is Glucose-6-Phosphate made into Fructose-6-phosphate in step 2?
This is done through sugar rearrangement
In they glycolytic pathway from glucose to pyruvate, how is Fructose-6-Phosphate converted into Fructose-1, 6 Bisphosphate?
Through the enzyme Phosphofructo kinase and the input of ATP to produce ADP
In they glycolytic pathway from glucose to pyruvate, What does Frutose-1, 6 Bisphosphate become in step 4?
Dihydroxyacetone Phosphate
In they glycolytic pathway from glucose to pyruvate, What does dihydroxyacetone phosphate become in step 5?
Glyceraldehyde-3-phosphate
In step 6 of the Glycolytic pathway from glucose to pyruvate, What do the two molecules of Glyceraldehyde-3-phosphate become?
2 molecules of 1, 3 bisphosphoglycerate
What are the inputs and outputs to form 1,3 bisphosphoglycerate from Glyceraldehyde-3-phosphate?
Inputs: 2 Phosphate groups and 2 NAD+
Outputs: 2 NADH and 2 H+
Glycolytic pathway Step 7: 2molecules of 1, 3 Bisphosphoglycerate becomes..... And what are the inputs and outputs?
2 molecules of 3-phosphoglycerate. Inputs: 2 ADP Outputs: 2 ATP
Glycolytic pathway: 2 molecules of 3-phosphoglycerate becomes...
2 molecules of 2-phosphoglycerate
Glycolytic pathway: In step 9 2 molecules of 2-Phosphoglycerate becomes.....?
2 molecules of phosphoenolpyruvate
In step 10 of the Glycolytic pathway, 2 molecules of Phosphoenolpyruvate becomes ....? What are the inputs and outputs?
2 molecules of pyruvate
Inputs: 2 ADP
Outputs: 2 ATP by SLP
In the Glycolytic pathway, what causes the regeneration of NADH?
Pyruvate
How many ATP are produced in Glycolysis?
2 ATP
What is the primary goal of Glycolysis?
To recycle NAD+ and continue the process
What is an allosteric enzyme?
Means self regulating
What promotes the enzyme Phosphofructokinase?
AMP
High Levels of these ______ _______ _______ will inhibit the enzyme phosphofructokinase. Where does this inhibition take place on the enzyme? What step on the Glycolytic pathway is this?
ATP, NADH, and Citrate will inhibit the enzyme. Inhibition takes place on the active site. It is step 3.
In step 10, the enzyme pyruvate kinase is inhibited by:
Increase in ATP and Increase in Acytel CoA