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33 Cards in this Set
- Front
- Back
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Centrally located organelle of animal cells that is primary microtubule-organizing center and acts as the spindle pole during mitosis.
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Centrosome
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Protein from which microtubules are made
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Tubulin
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Protein complex in centrosomes that nucleates microtubule assembly.
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Gamma -tubulin ring
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Form the organizing centers for microtubules in cilia and flagella
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basal bodies
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Organelle positioning in the cell
Chromosome segregation Intracellular trafficking |
Microtubules
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Determines cell shape
Involved in whole cell movement |
Actin
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Provides mechanical strength
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Intermediate filaments
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The microtuble shrinks because it has lost its?
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GTP cap
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GTP > GDP
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Microtubule growth
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GDP > GTP
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Microtubule Shrinkage
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generally move towards the plus end (+)
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Kinesins
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generally move towards the minus end (-) toward the centrosome
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Dyneins
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organizing center for the cilium
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basal body
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Troponin cannot bind to actin without ?
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Tropomyosin
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Detachment of the myosin head from actin which is a result of?
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ATP hydrolysis.
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When skeletal muscle contracts what happens?
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Z discs come closer together
Sarcromeres become shorter. |
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When muscle cells contract
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because sudden increase of Ca 2+ into cytosol from the release of calcium from SR
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Intermediate filaments in epithelia (most diverse group)
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Keratin
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Intermediate found in connective tissue , Muscle cells, glial cells
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vimentin
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intermediate filaments found in Nerve cells
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neurofilaments
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in all animal cells (nucleus) Intermediate filaments?
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nuclear lamins
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Drug that binds and stablizes microtubules
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Taxol
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drug that bind subunits and prevents polymerzation
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colchicine/vinblastine
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Hair-like structures at the plasma membrane
Move fluid over the cell (food acquisition) Propel cells through a fluid (locomotion) Found on cells that line the respiratory tract |
cilia
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Similar to cilia but longer
Whole cell movement Regular wavelike motion (Not the same as the bacterial flagellum) |
Flagella
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bind to actin monomers
preventing polymerization |
Thymosin and profilin
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(ARPs) nucleate actin
filaments to form branched structures |
Actin related proteins
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severs actin
filaments converting actin from a gel-like state to a more fluid state |
Gelsolin
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binds along
the length of actin filaments influencing the association of actin binding proteins |
Tropomyosin
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are ATP
dependent actin motor proteins |
Myosin,
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Specialized layer of cytoplasm on the inner face of the plasma membrane. In animal cells it is an actin-rich layer responsible for cell-surface movements
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Cell Cortex
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protein filament abundant in muscle cells
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Actin filament
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Responsible for the bending of cilia. undergo ATP dependent movement along microtubules.
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Dynein
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