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12 Cards in this Set

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Compare the structure and organisation of prokaryotic and eukaryotic cells

1-10 microns 10-100 microns


None Many


Cytoplasm Nucleus


0.004 pg 4 pg


Circular Linear


1000 20,000


70S 80S


Peptidoglycan None


None Extensive


Minutes Hours

1. Cell size


2. Organelles


3. DNA location


4. DNA amount


5. Genome


6. No. of genes


7. RIbosome


8. Cell wall


9. Cytoskeleton


10. Cell generation time

Explain the principle of selective toxicity of antibiotics. Give examples (3).

Targets processes and molecules unique to prokaryotes.


Penicillin inhibits peptidoglycan synthesis


Streptomycin, tetracyclines inhibit bacterial ribosome.

Describe the compartmentalisation of the eukaryotic cell as a segregation of function.

Outline the structure and function of the nucleus.


How large is a nucleus?


What is its function?

5-10 microns


Has nuclear envelope


Site for RNA and ribosome synthesis

Outline the structure and function of the mitochondrion.


How large is it?


Which cells are abundant in mitochondria?

0.5-2 microns


Variable number in a cell - depends on energy requirements


Abundant in metabolically active cells - muscles and brown adipose tissue


Double membrane


Outline the structure and function of the rough ER

Active ribosomes attached to the membrane


Continuous with the nuclear envelope


Extent or RER depends on how much protein secretion a cell is doing

Outline the structure and function of the Golgi apparatus.

Modification of proteins


- protein phosphorylation


- addition of sugar residues


- proteolysis


- sorting of lipid and protein


Release of secretory vesicles0.5-2

Outline the structure and function of the transport vesicle

Bud off the RER and transport proteins through the cytoplasm to the Golgi apparatus

Outline the structure and function of the smooth ER

Tends to be more circular


No ribosomes attached to the membrane


Synthesis and processing of lipids

Outline the structure and function of the lysosome

Contains hydrolase enzyme that breaks down macromolecules


pH of lysosomes is maintained at 5


Destructive enzymes are only active in an acidic environment

Evaluate the selective advantages of eukaryotic cells.

Has compartmentalisation- special environments


High membrane surface area



Why are viruses immune to antibiotics?

Viruses are not a cell