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16 Cards in this Set
- Front
- Back
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In foetal life, haemopoiesis takes place in what organ?
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The liver
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Give an example of two regulatory factors of haemopoiesis in the bone marrow.
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Growth factors (e.g. Granulocyte-colony-stimulating factor (G-CSF)) and accessory cells (e.g. adipocytes, fibroblasts, osteoblasts, osteoclasts, endothelial cells)
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What is the action of G-CSF on progenitor cells?
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It increases production of neutrophils
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Growth factor that increases production of neutrophils
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G-CSF
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What are the five accessory cells in the bone marrow that help regulate haemopoiesis?
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Adipocytes, fibroblasts, osteolasts, osteoclasts, endothelial cells
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Adipocytes, fibroblasts, osteolasts, osteoclasts and endothelial cells can all be called _________ cells in the BM.
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Accessory
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What is the function of eosinophils?
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To kill antibody coated parasites.
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To kill antibody coated parasites describes the function of what cell?
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Eosinophils
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What is the function of basophils?
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To mediate immunological responses
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'To mediate immunological responses' describes the function of what kind of cell?
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The basophil
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What are the functions of monocytes?
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Differentiate into macrophages in tissues
Antigen presentation Phagocytosis |
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Which type of cell differentiates into a macrophage in the tissues?
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The monocytes
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What is the function of platelets?
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Form a haemostatic plug when a vessel wall is breached
Important in prevention of bleeding |
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Form a haemostatic plug when a vessel wall is breached
Important in prevention of bleeding |
Platelets
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Define 'neutropenic'
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A hematological disorder characterized by an abnormally low number of neutrophils
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A hematological disorder characterized by an abnormally low number of neutrophils
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Neutropenia
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