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32 Cards in this Set
- Front
- Back
What is the first line of somatic treatment for Tourette disorder?
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D2-antagonists
-Haloperidol -Pimozide |
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What is an effective alternative treatment for Tourette disorder if the side effects of Haloperidol/Pimozide inhibit you from being able to use them?
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Clonidine - alpha-2 agonists
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What are the diagnostic criteria of Tourette syndrome?
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-BOTH motor and vocal tics but don't have to occur at the same time
-At least 1 tic present daily for ONE YEAR, no 3-mo period of no tic -Onset before 18, signific distress |
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What is the inheritence pattern of Tourette disorder when it appears to be genetic?
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Autosomal DOMINANT
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What 2 mental disorders are often comorbidly present with Tourette syndrome?
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-OCD
-ADHD |
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What should be ruled out in the workup for Tourette syndrome?
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Allergies
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What are Slow, irregular writhing movements called?
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Athetoid
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What are Dancing, random, irregular, nonrepetitive movements?
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Choreiform
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What are Twisting motions interspersed with prolonged states of muscle tension and slower than choreiform movements called?
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Dystonic movements
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What are Intermittent, Coarse, Large-Amplitude, Unilateral limb movements called?
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Hemiballistic movements
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What are Brief, Shocklike muscle contractions called?
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Myotonic movements
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What are Sudden, rapid, recurrent, nonrhythmic, stereotyped MOTOR movements or vocalizations called?
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Tics!
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What is the lifetime prevalence of Tourette syndrome in the general population?
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4-5/10000
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What sex is Tourettes higher in?
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Males
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At what age do the motor vs vocal tics tend to appear?
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Motor - 7
Vocal - 11 |
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What NT system is involved in tic disorders?
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DOPAMINERGIC
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What are 4 medical conditions in which involuntary movements can be seen?
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-Sydenham chorea
-Huntington chorea -Wilson disease -Stroke |
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What drug can cause tardive dyskinesia after long-term use?
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Antipsychotics like Haloperidol
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What is the time duration for diagnosis of a TRANSIENT tic disorder?
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>4 weeks but not 1 year
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What is it called if a patient has tics for >1 yr, but not both motor and vocal?
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Chronic motor or vocal tic disorder
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What is often a trigger to tics in children?
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Anxiety-producing events
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What does the treatment of Tourette disorder involve?
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BOTH somatic drug therapy and psychotherapy
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What type of psychotherapies can help in Tourette disorder?
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Relaxation techniques
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What are the 2 first line drugs currently for treating the tics in Tourettes?
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-Clonidine
-Guanfacine |
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Why aren't Haloperidol and Pimozide first line?
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Bc of side effects and risk of tardive dyskinesia with long term use
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With what other medications are the development of Tics a common side effect?
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Stimulants for ADHD
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What should be done if a patient with ADHD is on a stimulant like methylphenidate and develops motor and/or vocal tics?
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Reduce the dose of methylphenidate
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What is Amenorrhea defined as?
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Absence of menstrual cycles for at least 3 consecutive months
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What is Anorectic body weight considered to be?
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Body weight <85% normal for the patient's age, produced by conscious efforts to lose weight
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What is the fine body hair present on prepubertal children and often seen in anorexic patients called?
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Lanugo
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What are the 4 diagnostic criteria for Anorexia nervosa?
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-Refusal to maintain normal bodyweight
-Intense fear of gaining weight -Distorted body image -Amenorrhea |
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What are common lab abnormalities in patients with Anorexia nervosa?
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-Hypokalemia
-Hypochloremic metabolic acidosis -Hypoalbuminemia -Elevated liver enzymes -Neutropenia w/ rel lymphocytosis |