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56 Cards in this Set
- Front
- Back
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BP
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hard to say/complex (not asked on this set) however, interstitial volume increases (as indicated by the edema in the limbs)
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HR
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increase
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GFR
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decrease bc the disease and thickening of the membrane
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ADH
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decrease
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Aldosterone
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decrease
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Ang II:
Renin: |
decrease
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ANP/BNP
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increase
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blood pH
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low
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urinary pH
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low
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urinary HCO3
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low, very low because of lack of H+ secretion, excess H+ will turn hydrogen into H2CO3. Metabolic acidosis
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urinary NH4
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high
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proteinuria
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increase
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resp rate
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increase
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hematocrit
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low
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epinephrine/norepinephrine:
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increase
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vasoconstriction in peripheral vessels
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NO will decrease, maybe vessels are a little more dilated?
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acetylcholine
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no
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antibodies
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yes
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liver function
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yes
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WBC
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increase, due to infection recognized by macrophages that release colony stimulating factors
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colony stimulating factors (from macrophages):
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increase
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interlukin1/6/TNF alpha:
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increase
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TNF alpha
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increase
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H2O permeability of glomerular membrane:
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decrease
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interstitial volume:
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increase
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NO in blood vessels:
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down(released only in healthy endothelium- all are damaged, esp throat), less dilation, lots of cytokines released and Arachnadonic acid metabolites in the throat and kidney.
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inflammation of throat and kidney:
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increase
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arachidonic acid metabolites:
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increase
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free arachodonic acid:
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increase
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Clotting
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increase, due to endothelium damage (factors in endotheium that prevent clotting: NO, prostacycline, TPA, ADP-ase= all decrease)
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prostacycline
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down
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Tissue plasminogen activator
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decrease (released from healthy endothelium )
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ADP
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: increase, causes increase in platelet activation
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ADPase
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decrease
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Mast cell degranulation:
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increase (especially in throat and kidney)
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Histamines
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increase
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prostaglandin
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increase
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prostacyclin
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decrease
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chemotactic factors
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increase
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inflammation in the kidney
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: due to antibody immune complexes. No actual infection, just inflammation of kidney (this is what effects GFR- overall membrane is thicken, but slits are larger- more protein in urine)
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leaking of protein:
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increase
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arterioles
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dilate
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Capillaries
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increase permeability due to contraction of endothelium
leaky |
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Bicarbonate
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low
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Hydrogen
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increase (destroy the bicarbonate) = Metabolic acidosis, respiratory compensation kicks in immediately
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Total Body Sodium:
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(massive edema) increase
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Total Body Water:
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increase
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inulin clearance
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low (measure of GFR)
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creatinine clearance
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decrease
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body temp:
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increase (fever) reset set-point in hypothalamus by increase in PGE2
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sedimentation rate (SED) of RBC
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increase, diagnostic of inflammation
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clotting
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increase, this increases SED rate
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roeulle formation:
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low
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fibrin
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up
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acute phase proteins from liver
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increase (CRP and 100 others), increased due to cytokines
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B-cells/T-cells:
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(significant/specific ones increase) total number probably won’t increase, but specific b and t cells for this infection will increase.
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