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43 Cards in this Set

  • Front
  • Back
What is biofilm?
A community of bacteria in a sticky matrix of mucopolysaccharide polymers
What does biofilm do?
Greatly enhances the survivability of the microorganisms

Biofilms have fluid channels near the enamel that allow nutrients, oxygen, and waste to travel
What dietary factors increase biofilm?
Sucrose
How is biofilm formation described as?
Organized
How soon does pellicle form on the tooth?
30 minutes (to 2 hours)
What is the transparent zone in dentinal caries? Can it remineralize? Is the collagen matrix intact?
Zone 3 out of 5 zones (from deepest to most superficial)
No bacteria present

Initial site of acid attack of organic material

Collagen matrix is still intact
Template allows for re-mineralization/self-repair
What is the difference between affected and infected dentin?
Affected dentin: Zones 1-3 (deepest)
Softened and demineralized, but not yet invaded by bacteria
Collagen infrastructure still intact

Infected dentin: Zones 4 and 5 (superficial)
Softened and contaminated with bacteria
No collagen infrastructure
Is calculus mainly inorganic???? What covers it?
Mostly composed of mineralized calcium phosphate (mineralized plaque)
Covered by a dental plaque, which can contribute to the calculus
What is the sequence (hardest to softest between enamel, dentin and cementum?
Hardest to softest:
Enamel, dentin, cementum
What is prevalence? Incidence? Is the prevalence of caries declining in developing countries? How about less developing countries? Is it epidemically increasing in emerging economies?
Prevalence: Number of individuals in a population having a disease at a specific time

Global prevalence:
Developed countries - decreasing
Less-developed countries - increasing
Emerging economies - epidemically increasing

Incidence: Number of new cases of the disease
What is DMFS?
DMFS - Decayed, Missing, Filled Surfaces

Distinguish from DMFT - decayed, missing, filled teeth
Adults
Dmfs (0-128 surfaces)
Dmft (0-28 teeth)

Children
Dmfs (0-88 surfaces)
Dmft (0-20 teeth)
At what pH will subsurface enamel begin to be removed into solution?
At a pH of 5.5 or lower
What is the primary way a host controls oral flora?
Saliva is the primary means by which the host exerts control over oral flora
In saliva, bicarbonate buffers Acids at what pH?
5.5
Is strep sanguis early or late? Strep salivarius?
Strep sanguis
Initial tooth colonizer
Early

Strep salivarius
Early colonizer
Found on the dorsum of the tongue
Late
Does plaque go from anerobic to aerobic as it develops or vice versa?
Vice versa - bacteria transition from aerobic to anaerobic as the plaque develops
What do streptococcal glucosyltransferases make that makes strep mutans sticky?
Glucans
What do statherins do in saliva? What do they for teeth?
Prevents precipitation of calcium phosphate
Keeps calcium and phosphate dissolved in solution
What do glycoproteins(mucins) do to bacteria?
Agglutination facilitates bacterial clearance
Cause bacteria to clump together

Also called Non-immunoglobulin agglutinins
What bond does Lysozyme cleave?
Lysozyme cleaves Beta-1,4 bonds
-NAG (N-acetylglucosamine)
-NAM (N-acetylmuramic acid)

Degrades bacterial cell walls
-Releases peptidoglycans that activate the complement system
What happens to the saliva of a patient with Sjogren’s syndrome?
Xerostomia
-Autoimmune disorder affecting salivary and lacrimal glands
How would you treat that patient with xerostomia?
Stimulate flow
-Sugar-free gum
-Raw vegetables
-Parasympathomimetic drugs (pilocarpine) - this is what you could prescribe

Saliva substitutes
Regular fluoride therapy
Immaculate oral hygiene
Increased consistent water consumption
One of the risks from using a live attenuated vaccine of strep mutans is...
Rheumatic fever
What is mineral weight of enamel, dentin in percentages?
Enamel: 95-98%
Dentin: 70%
What bodily substance is cementum most closely related to?
Bone
What are Tomes fibers?
Extensions of odontoblasts into dentinal tubules

Distinguish from "Tomes process", which form enamel rods
Does enamel have collagen?
No
What are stria of retzius?
Incremental growth lines representing specific times of enamel matrix mineralization
Represent "weekly rhythm" of ameloblasts
Higher organic content
-Distinguish from "cross striations" - represent daily enamel matrix secretion
What are enamel tufts
Like geologic faults
Extend from the DEJ to about 1/3 to 1/2 the thickness of enamel
Hypomineralized
No known clinical significance
What are perikymata?
Grooves and elevations on the tooth surface
What are enamel lamellae
Extend from the surface of the enamel to varying depths
Hypomineralized
Look like enamel tufts
Linear, longitudinally oriented
Contain organic material
What are enamel spindles?
Trapped odontoblast processes that extend into the enamel from the DEJ
What type of caries is more common in elderly patients?
Root Caries
Which of the zones of the uncavitated enamel lesions has the largest, smallest pore volumes?
Smallest pores:
Translucent zone (deepest) - Zone 1
Pore volume: 1%

Largest pores:
Body of lesion (just below surface zone) - Zone 3
Pore volume: 5-25%
What are the lines of von Ebner?
Daily incremental growth lines of dentin
-Distinguish from "contour lines of Owen" which are analagous to Stria of Retzius in dentin
What are the charisteristics of caries? Is it multifactorial infectious, chronic?
Definition : An infectious, multifactorial, microbiologic disease of the teeth that results in localized dissolution and destruction of the calcified tissues

Probably the most common chronic disease
In caries what factors combined determine the process of caries?
Four factors:
Host (tooth, saliva)
Microflora (bacteria)
Substrate (diet)
Time
Would you use a narrow spectrum antibiotic if you believed in the non specific plaque hypothesis?
No, the non-specific plaque hypothesis says that all plaque is bad and relentless effort must be made to keep the mouth free of all bacteria.
Does the specific plaque theory feel plaque is not a normal phenomena?
No, the specific plaque theory says that plaque is normal, even in the absence of disease
A believer of this hypothesis would use narrow spectrum oral antibiotics
Ecologic plaque theory?? Can good and bad plaque coexist?
The ecologic plaque theory says that cariogenic and non-cariogenic co-exist and balance in a plaque
How long does it take for mature plaque colonies to form?
Two weeks for mature plaque colonies to form
What is the critical pH in saliva?
Teeth decalcify at pH 4.0
“Any acid with a pH below the critical pH of dental enamel (5.5) can dissolve the hydroxyapatite crystals in enamel.”
What does diet or regular cola do a tooth?
Extrinsic acids erode the tooth