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12 Cards in this Set

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ANOREXIA-CACHEXIA SYNDROME
effect of CA cells on metabolism: CA cells divert nutrition to own use and inhibit food intake; they also break down body tissue and muscle proteins to support their growth.
CANCER
disease that results when normal cells mutate into abnormal ones and continue to reproduce within the body.
CARCINOGENS
cancer-causing agents
METASTASIS
process by which malignant neoplasms spread to distant sites; a secondary tumor formed by this process
NEOPLASM
tumor; mass of abnormal cells that grows independently of its surrounding structures and has no physiologic purpose
ONCOGENES
genes capable of triggering CA
ONCOLOGY
study of CA
WHAT can cause GENETIC MUTATION of the cells?
aging, exposure to chemicals, radiation, hormones, smoking

OVER TIME- many gene mutations may occur in a cell, permitting it to divide and grow in a way that eventually leads to CA
What are CHARACTERISTICS of CA cells?
+ vary in size and shape
+ aren't encapsulated
+ undergo abnormal mitosis
+ function abnormally
+ don't resemble their cells of origin
+ produce substances rarely associated with the original cell or tissue
= can spread to other sites
What is UNCONTROLLED LOCALIZED GROWTH?
UNLIKE normal cells, CA cells keep growing and multiplying even after lost cells have been replaced.
How is CA CLASSIFIED?
by the tissues or blood cells in which it originates. MOST CA derive from epithelial tissues and are called carcinomas. OTHER CA arise from THESE tissues and are called: glandular (adenocarcinoma); connective, muscle, bone (sarcoma); brain, cord (glioma), pigmented cells (melanoma), lymphatic tissue(lymphoma), leukocytes (leukemia), erythrocytes (erythroleukemia)
ACUTE LEUKEMIA
cancerous WBC precursors called blasts proliferate in the bone marrow or lymph tissue and then accumulate in peripheral blood, bone marrow, and body tissues. Untreated, leukemia invariable leads to death, usually from complications of leukemic cell infiltration of bone marrow or vital organs. Among CHILDREN, leukemia is the most common CA