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19 Cards in this Set
- Front
- Back
What are the 3 opioid receptors?
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1. mu
2. delta 3. kappa |
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Which of the opioid receptors is the main one?
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mu receptors
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What are the 3 endogenous opioids?
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1. enkephalins
2. dynorphins 3. endorphins |
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What are the 5 natural opioid agonists?
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1. morphine
2. heroin 3. hydromorphone 4. codeine (and codeine containing mixtures) 5. hydrocodone |
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What is the prototypical mu opioid?
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morphine
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What are the 4 synthetic opioid compounds?
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1. meperidine (demerol)
2. fentanyl 3. methadone 4. propoxyphene (darvocet) |
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What are the 2 opioid antagonists?
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1. naloxone
2. naltrexone |
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What are the 6 opioid mixed agonist-antagonists?
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1. pentazocine
2. butophanol 3. nalbuphine 4. dezocine 5. buprenophine 6. tramadol |
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Which opioid can also be used for neuropathic pain?
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tramadol
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What are the signs of opioid overdose?
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- pinpoint pupils
- decreased respiration - loss of consciousness |
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What is differential tolerance?
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occurs when a person is only tolerant to one effect of the drug (not all of them)
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What are the desirable properties of morphine?
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- effective analgesia over a wide dosage range
- effect on mood (relief or anxiety)(euphoria) - sedation |
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When opioids and _______ are given together, there is a synergistic effect.
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NSAID's
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A drug ending in -dan is an opioid and ______.
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aspirin
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A drug ending in -cet is an opioid and ________.
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acetaminophen (tylenol)
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Opioids don't work well for ________ pain.
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neuropathic
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anything coming from the poppy seed (natural) is called
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opiate
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natural and synthetic opioids are called
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opioid
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Which partial agonist can be used to replace methadone?
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buprenorphine
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