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19 Cards in this Set

  • Front
  • Back
What are the 3 opioid receptors?
1. mu
2. delta
3. kappa
Which of the opioid receptors is the main one?
mu receptors
What are the 3 endogenous opioids?
1. enkephalins
2. dynorphins
3. endorphins
What are the 5 natural opioid agonists?
1. morphine
2. heroin
3. hydromorphone
4. codeine (and codeine containing mixtures)
5. hydrocodone
What is the prototypical mu opioid?
morphine
What are the 4 synthetic opioid compounds?
1. meperidine (demerol)
2. fentanyl
3. methadone
4. propoxyphene (darvocet)
What are the 2 opioid antagonists?
1. naloxone
2. naltrexone
What are the 6 opioid mixed agonist-antagonists?
1. pentazocine
2. butophanol
3. nalbuphine
4. dezocine
5. buprenophine
6. tramadol
Which opioid can also be used for neuropathic pain?
tramadol
What are the signs of opioid overdose?
- pinpoint pupils
- decreased respiration
- loss of consciousness
What is differential tolerance?
occurs when a person is only tolerant to one effect of the drug (not all of them)
What are the desirable properties of morphine?
- effective analgesia over a wide dosage range
- effect on mood (relief or anxiety)(euphoria)
- sedation
When opioids and _______ are given together, there is a synergistic effect.
NSAID's
A drug ending in -dan is an opioid and ______.
aspirin
A drug ending in -cet is an opioid and ________.
acetaminophen (tylenol)
Opioids don't work well for ________ pain.
neuropathic
anything coming from the poppy seed (natural) is called
opiate
natural and synthetic opioids are called
opioid
Which partial agonist can be used to replace methadone?
buprenorphine