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5 Cards in this Set
- Front
- Back
What are the three different types of hormones regarding solubility?
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- Lipid soluble hormones that are bound to protein carriers and are temporarily water soluble and bind to receptors inside the cell
-Unbound lipid soluble hormones that are free in plasma and can bind to receptors - Water soluble hormones are free in plasma and need no carriers and bind to receptors on the cell surface |
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What is the most common cause of SIADH (posterior pituitary dysfunction)?
What are other causes? |
- Most common is small cell CA in the lung
- Other causes are CNS disorders (trauma, CVA, brain surgery), drugs (anesthesia, narcotics), stressors (pain, fear, surgery, trauma) |
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What are the clinical manifestations of SIADH?
What are the treatments? |
- Manifestations include: Hyponatremia (causes swelling of the tissues, esp. the brain), hypo-osmolarity, decreased urine output, concentrated urine
- Treatments include: Fluid restrictions, monitor daily weight, monitor I&O, monitor serum Na+, monitor neurological manifestations through the Glascow Coma Scale |
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What are the manifestations of Hyponatremia?
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- Manifestations include swelling of the tissues, esp. of the brain, which present through anorexia, vomiting, fatigue, dulled sensorium, lethargy, seizures, coma
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SAIDH case study:
58-yr-old female admitted 24 hours ago with small cell CA, hyponatremia, HA, confusion. Na+ 115 on admission. Nursing report this am: confused as to time and place, slight HA last night, A&O x3, Na+ ordered for this am, IV NS 50 mL/hr, fluid restriction 1,500 mL/day - What will you assess this am? Why will you assess it? Interpret the meanings of the findings. What will you assess about pt/family knowledge? |
-What - Orientation x3, HA, GCS, pupil size/reaction, strength in hands and feet, I&O, ask about thirst
- Why - These assess neurological functioning - Interpretation - Lung CA can produce ADH, very low Na+ may result in brain swelling - Educate pt and family about fall hazards, tx is restriction of fluids, monitoring thirst, pt may suck on hard candy (sugar- free) |