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7 Cards in this Set
- Front
- Back
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Thrombolytics activate
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plasminogen, which generates plasmin to dissolve clots
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Used early in which disease?
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MI, within 4-6 hours of onset of infarct
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Also used for other disease processes?
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arterial thrombosis, DVT, occluded shunts, and PE
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Contraindicated in?
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hemorrhagic brain stroke, intracranial or intraspinal surgery within last 2 months, thoracic or abd surgery in last ten days, uncontrolled HTN, recent CPR
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Name 5 thrombolytic medications.
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alteplase (tPA), reteplase, streptokinase, tenecteplase, Urokinase
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Interventions
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Monitor for hypotension, tachycardia, altered mental status, apply direct pressure over puncture site for 20-30 minutes
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Antidote for streptokinase?
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Amicar
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