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19 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Name the HMG-CoA reductase inhibitors
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Lovastatin
Pravastatin Simvastatin Atorvastatin |
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MOA HMG-CoA reductase
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Inhibit, cholesterol precursor, Mevalonate
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pg 268
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MOA Niacin
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Inhibits lipolysis in adipose tissue
Reduces hepatic VLDL secretion into circulation |
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Name the bile acid resins
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Cholestyramine
Colestipol |
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MOA bile acid resins
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prevent intestinal reabsorbtion bile acids;
liver must use cholesterol to make more |
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Name the cholesterol absorption blockers
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Ezetimibe
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MOA Ezetimibe
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Prevent cholesterol reabsorption at small intestine brush border
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Name the fibrates
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Gemfibrozil
Clofibrate Bezafibrate Fenofibrate |
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MOA Fibrates
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upregulate LPL to increase TG clearance
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Name the drug that has the best effect on LDL
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Lovastatin
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Name the drug that has the best effect on HDL
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Niacin
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Name the drug that slightly increases TG
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Bile acid resins
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Name the drug that has the best effect on triglycerides
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Fibrates
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Statin and Fibrates will cause an increase rk for what?
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Rhabdomyolysis secondary to muscle injury
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What is the treatment for pts at risk for rhabdomyolysis
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Isotonic fluids
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Name the adverse effects of HCTZ
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Hypokalemia metabolic alkalosis
Hyponatremia mild hyperlipidemia hyperuricemia lassitude hypercalcemia hyperglycemia |
hyperGLUC
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Name the adverse effects of loop diuretics
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Ototoxicity
Hypokalemia Dehydration Allergy (sulfa) Nephritis Gout Metabolic alkalosis |
O.H. D.A.N.G
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Name the hypertensive drugs that decrease sympathetic outflow (sympathoplegics)
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Clonidine
Reserpine Beta blockers Methyldopa Prazosin Guanethidine Hexamethonium |
Sympathoplegics
Can't Resist Breaking My Puppy's Giant Heart |
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Name the preferred initiation of anti-hypertensive tx
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Hydrochlorothiazide
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