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36 Cards in this Set

  • Front
  • Back
STEMI treatment algorithm (for symptoms LESS than 12 hours) (6)
1)ASA & Nitro SL/IV
2)Clopidogrel 300mg
3)reperfusion therapy (PCI or fibrinolytics)
4)if using PCI follow w/ UFH, enox, GP2b/3a inhibitor
5)if using fibrinolytics follow w/ UFH, enox, fondaparinux
6)last step is put on BB, statins, ACEI/ARB, sprinonolactone
STEMI treatment algorithm (for symptoms MORE than 12 hours) (4)
1)ASA/Nitro SL/IV
2)stress test/PCI/CABG
3)clopidogrel
4)finally BB, statin, ACEI/ARB, sprionolactone
Eptifibatide brand
Integrillin
Abciximab brand
ReoPro
Bivalirudin brand
Angiomax
Fondaparinus brand
Arixtra
Treatment of STEMI uses what drugs? (6)
1)ASA
2)Nitro (morphine can be used on top of this for angina pain)
3)plavix
4)UFH, enoxaparin, fondaparinux
5)BB
6)thrombolytics
a)First generation thrombolytics
b)2nd generation thrombolytics
c)3rd generation thrombolytics

AND WHICH IS MOST FIBRIN SPECIFIC
a)streptokinase
b)alteplase
c1)reteplase*****
c2)tenecteplase*****
Typical QUALITY (desc) features of angina due to CAD (7)
1)discomfort (rather than pain)
2)crushing/pressure
3)squeezing
4)strangling
5)heaviness on chest
6)burning
7)NOT sharp or stabbing
Typical LOCATION features of angina due to CAD (5)
1)retrosternal
2)visceral
3)across chest
4)diffuse
5)sometimes jaw, neck, arms only
Typical RADIATION features of angina due to CAD (6)
1)to left shoulder or arm (CLASSIC)
2)sometimes right arm or both arms
3)neck, jaw, teeth
4)back
5)epigastrium
6)NOT below umbilicus or on top of head
Typical DURATION features of angina due to CAD (3)
1)30sec to 30min
2)waxing and waning
3)NOT continuous for hours
Typical PRECIPITATING FACTORS features of angina due to CAD (4)
1)exercise/exertion
2)emotional stress
3)cold weather
4)ANYTHING that increases oxygen demand
Typical RELIEVING FACTORS features of angina due to CAD (4)
1)rest
2)nitro
3)ANYTHING that reduces cardiac workload
4)NOT antacids, NSAIDs or change in position
ABSOLUTE CI to thrombolytics (7)
1)intracranial hemorrhage
2)known cerebral vascular lesions
3)known intracranial neoplasm
4)ischemic stroke within 3 months
5)suspected aortic dissection
6)Active bleeding or bleeding diathesis
7)significant closed head or facial trauma within 3 months
RELATIVE CI to fibronilytics (9)
1)uncontrolled HTN
2)ischemic stroke (greater than 3months ago)
3)dementia
4)traumatic/prolonged CPR
5)major surgery less than 3wks ago
6)recent (2-4wks) internal bleed
7)pregnancy
8)active peptic ulcer
9)current warfarin use
Componenets of TIMI risk score (6)
1)over 65yo
2)more than 3 coronary risk factors
4)ST-segment deviation
5)more than 2 angina events within 24hrs
6)use of ASA within 7 days
7)elevated cardiac markers
Risk according to TIMI score (3)
1)0-2 low risk
2)3-4 intermediate risk
3)5-7 high risk
Management strategies of unstable angina/NSTEMI (2)
1)early invasive strategy
2)early conservative strategy
Early invasive strategy (4)
1)Cardiac cath done in order to....
2)perform a PCI w/o first getting...
3)a noninvasive stress test OR
4)w/o failing medical treatment
Early conservative strategy (6)
0)medically manage ACS w/ antiplatelet & anti-coag
1)cardiac cath performed ONLY if...
2)persistent or recurrent chest pain
3)depressed LV fxn
4)malignant ventricular arrhythmia
5)high-risk physiologic stress test (+ on it)
Drugs used to treat unstable angina/NSTEMI (9)
1)ASA/plavix
2)nitro SL/IV
3)UFH/enox/fondaparinux
4)bivalirudin
5)GP2b/3a inhibitor
6)BB
7)statins
8)ACEI/ARB
9)sprionolactone
Secondary prevention medications used to reduce long-term mortality (6)
1)ASA
2)plavix
3)ACEI
4)aldosterone
5)BB
6)statins
How to treat PRIMARY IHD (9)
1)lipid lowering therapy
2)HTN management
3)DM management
4)smoking cessation
5)antiplatelet therapy
6)Type A personality
7)post-menopausal
8)binge drinking (moderate drinking is NOT a RF)
9)diet/exercise
How to treat SECONDARY IHD (5)
1)treat anginal/ischemic episode via Nitro
2)use anti-platelets
3)Maintenance of anginal pain symptoms (via BB (first line) or CCB (2nd) or long acting nitrates (3rd))
4)Ranolazine for anti-ischemia
5)PLUS ABCDE APPROACH
Secondary intervention goals (2)
1)prevent development of complications from MI (heart failure, arrhythmias, etc)
2)reduce symptoms of angina
Major CV risk factors by NCEP and JNC (9)
1)smoking
2)HTN
3)low HDL (less than 40)
4)elevated TC and LDL
5)age (over 45men; over 55women)
6)family history of premature heart disease (1st degree male before 55; 1st degree female before 65)
7)inactivity
8)DM (this is considered an "equivalent" risk of an event as someone who has already developed IHD)
9)HDL over 60 is a NEGATIVE risk factor
CV effects of smoking (7)
1)incr HR
2)incr BP
3)impaired O2 to heart b/c of carbon monoxide from smoke
4)negative inotrope
5)incr platelet adhesion
6)decr threshold for arrhythmias
7)impaired endothelial fxn
2 primary goals for treating pts @ risk for IHD (primary prevention)
1)prevent pt development of IHD
2)modify pt risk factors for development of IHD
When should a pt @ risk for IHD get anti-platelet therapy?
pt w/ 10year risk of a cardiac event if greater than 10%
General treatment strategies for management of chronic stable angina (3)
1)Nitro for acute ischemic attack
2)anti-platelets
3)BB, CCB, long acting nitrate for maintenance of anginal pain
ABCDE approach in SECONDARY IHD prevention
A)anticoag, ACEI/ARB, anti-anginals
B)BB, BP
C)cholesterol manage, cig smoking, cardiac revascularization
D)DM, diet
E)education, exercise
Nitro pt counsel points (6)
1)keep in original container, tightly closed
2)Once SL nitro is opened, it is only good for 6months
3)Not addictive
4)take @ onset of chest pain
5)inadequate saliva may interfere w/ absorption of SL nitro
6)HA and sublingual tingling are common ADR's
Pharmacological effects of BB in secondary prevention of IHD (5)
1)decr oxygen demand
2)decr HR, contractility, BP
3)incr wall tension
4)improves exercise duration
5)delays ST segment changes
Pharmacological effects of CCB in secondary prevention of IHD (6)
1)vasodilation of arterioles and coronary arteries
2)decr arterial pressure
3)decr coronary vascular resistance
4)decr contractility
5)decr conduction velocity of SA/AV nodes
6)inhibits coronary artery vasospasm
Pharmacological effects of long acting nitrates in secondary prevention of IHD (4)
1)decr oxygen demand by reducing venous return
2)dilates coronary arteries
3)incr oxygen supply due to vasodilation
4)inhibits vasospasm