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33 Cards in this Set
- Front
- Back
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Furosemide
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Diuretic
inhibits co-transporter of Cl in loop of henle, with loss of Cl, Na, K, H20, Ca, Mg into urine. |
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Spironolactone
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Diuretic
K/Mg sparring that antagonizes aldosterone in distal collecting duct |
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Hydrochlorothiazide
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Diuretic
Blocks Na transporter in distal conv. tubule |
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Nesiritide
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Diuretic
human brain naturetic factor |
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Digoxin
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Inotrope
inhibits Na-K pump activating Na-Ca exhanger to increase Ca influx. Also sensitizes baroreceptors |
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Catacholamines (dopamine, dobutamine) Low/high dose effects?
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Inotrope
Stimulate cardiac beta and alpha receptors via increased Camp or IP3 respectively. Low dose-stimulates B2 vasodilation, High dose stimulates A vasoconstriction |
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Milrinon/Amrinone
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Inodilator
PDE-III inhibitors to prevent Camp breakdown |
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Pimobendin
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Ca Sensitizer
PDE-III inhibitor/vasodilator |
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Nitroglycerine
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Vasodilator
NO mediated smooth muscle VD. systemic venodilator |
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Sodium Nitroprusside
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Vasodilator
NO mediated smooth muscle VD. systemic arerial/venous dilator |
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Sildenafil
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Vasodilator
Inhibits PDE-V to increase CGMP for pulm and arterial VD |
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Hydralazine
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Vasodilator
Alters K channels in Vasc smooth muscle for arterial VD |
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*pril 3 modes of action
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ACEI
blocks ATI-ATII, decrease aldosterone, may reduce symp activity |
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Benazepril
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ACEI
Eliminated by liver-good for CRF patients |
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*lol
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Beta blockers
decreased chrono, lusi, dromo, bathmo, inotropy. Also allow for vasodilation of blood vessels |
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1st gen Beta blockers
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nonselective -propranolol
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2nd gen beta blockers
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selective b1 blockers metoprolol and atenolol
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3rd gen beta blockers
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alpha blocking and anti-oxidant properties -carvedilol
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Hydrophilic beta blockers with renal excretion
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atenolol, nadolol, sotalol
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Atenolol
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b1 blocker, renal clearence, very popular beta blocker
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Metoprolol
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cardioprotection in K-9
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Esmolol
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nonspecific B-blocker with short duration of action due to hydrolyzation by plasma esterases
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Amlodipine
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CCB
Vasodilator |
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Diltiazem
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CCB
Antiarrhythmic for supraventricular arrhytmias |
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Antiarrhythmic
Class I |
Reduces Na influx by blocking Na channel
Quinodine/lidocaine/mexiletine |
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Antiarrhythmic
Class II |
beta blockers
*lol |
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Antiarrhythmic
Class III |
Block K channels
sotalol/amiodarone |
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Antiarrhythmic
Class IV |
Block calcium ions across slow Ca dependent channels
verapamil/diltiazem |
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Procainamide
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Antiarrhythmic
Broad spectrum for atrial or ventricular premature complexes |
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Quinidine
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Antiarrhythmic
atrial flutter in horses |
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Lidocaine/mexiletine
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Antiarrhythmic
Control ventricular tachycardia/arrhythmias in K-9 |
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Sotalol/Amiodarone
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Antiarrhythmic
Beta blocker effects, and blocks K channels (II + III) Amiodarone hepatic metabolism |
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Diltazem
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Antiarrhythmic
Blocks L-type Ca channels |
