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12 Cards in this Set
- Front
- Back
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Mechanism
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Bind PBPs
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Bacteriocidal or static?
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Cidal
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NDM1
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New Dehli
Resistan to carbapenams and almsot all antibiotics |
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Spectrum of activity
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Broad
Gram + and - |
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Resistance
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Beta-lactamases
PBP2a Increased efflux B-lactamase + efflux = high level resistance |
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Absorption
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Parenteral
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Distribution
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Most body tissues
CSF when meninges inflames |
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Metabolism
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Impenem
Other unchanged |
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Excretion
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Renal
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Clinical uses
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Very complicated disease
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Adverse effects
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Seizures
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Drug interactions
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Valproic acid
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